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  1. No Access

    Article

    Therapeutic role of kaempferol and myricetin in streptozotocin-induced diabetes synergistically via modulation in pancreatic amylase, glycogen storage and insulin secretion

    Kaempferol and Myricetin alone have promising benefits on diabetes and related complications, yet the effectiveness of cotreating the two compounds on diabetes have not been studied. The existing investigation...

    Fahad A. Al-Abbasi, Imran Kazmi in Molecular and Cellular Biochemistry (2023)

  2. No Access

    Article

    Sepsis triggered oxidative stress-inflammatory axis: the pathobiology of reprogramming in the normal sleep–wake cycle

    In individuals with sepsis-related neurodegenerative illness, sleep and circadian rhythm disturbance are common. The alteration in genomic expression linked with the immune-directed oxidative stress-inflammato...

    Waleed Hassan Almalki, Mohammed M. Ghoneim… in Molecular and Cellular Biochemistry (2022)

  3. No Access

    Article

    Biochemical interaction of salt sensitivity: a key player for the development of essential hypertension

    Worldwide, more than 1 billion people have elevated blood pressure, with up to 45% of adults affected by the disease. In 2016 the global health study report on patients from 67 countries was released in Lancet...

    Imran Kazmi, Waleed Hassan Al-Maliki, Haider Ali… in Molecular and Cellular Biochemistry (2021)

  4. No Access

    Article

    Alteration of serum immunoglobins, C-reactive protein, vitamin D, and electrolyte by atenolol and amlodipine in stress-induced hypertensive rats

    The present study is designed for the assessment of various pathological changes like immunoglobins, C-reactive protein, vitamin D, sodium, potassium, calcium in stress-induced hypertensive rats. Albino Wistar...

    Moayad Mustafa Hejazi, Ala Osman Bacha… in Molecular and Cellular Biochemistry (2018)

  5. No Access

    Article

    Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/β-catenin signaling pathway

    Hepatocellular carcinoma (HCC) is the fifth leading cause of death and is generally typified by elevated liver enzyme biomarkers, antioxidants, and chronic inflammation of hepatocytes. Although currently avail...

    Shakir Saleem, Ruqaiyah Khan, Muhammad Afzal… in Molecular and Cellular Biochemistry (2018)

  6. No Access

    Article

    Therapeutic exploration of betulinic acid in chemically induced hypothyroidism

    Hypothyroidism is a chronic condition characterized by abnormally low thyroid hormone production. The decreased serum level (>5.1 mIU/l) of thyroid-stimulating hormone (TSH) in blood indicates hypothyroidism....

    Muhammad Afzal, Imran Kazmi, Susmita Semwal… in Molecular and Cellular Biochemistry (2014)

  7. No Access

    Article

    Combination of sulfamethoxazole and selenium in anticancer therapy: a novel approach

    Sulfonamides have been reported to possess substantial antitumor activity as they act as carbonic anhydrase inhibitors. In addition, selenium appears to have a protective effect at various stages of cancer due...

    Ritu Gupta, Imran Kazmi, Muhammad Afzal… in Molecular and Cellular Biochemistry (2013)

  8. No Access

    Article

    Hepatoprotective potential of new steroid against carbon tetrachloride-induced hepatic injury

    The present study was designed to evaluate the hepatoprotective effects of newly isolated stigmast-4, 20 (21), 23-trien-3-one (STO) against carbon tetrachloride-induced hepatic injury in Wistar albino rats. He...

    Muhammad Afzal, Ruqaiyah Khan, Imran Kazmi… in Molecular and Cellular Biochemistry (2013)