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Article
Open AccessRetrospective validation study of an artificial neural network-based preoperative decision-support tool for noninvasive lymph node staging (NILS) in women with primary breast cancer (ISRCTN14341750)
Surgical sentinel lymph node biopsy (SLNB) is routinely used to reliably stage axillary lymph nodes in early breast cancer (BC). However, SLNB may be associated with postoperative arm morbidities. For most pat...
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Article
Open AccessThe implementation of a noninvasive lymph node staging (NILS) preoperative prediction model is cost effective in primary breast cancer
The need for sentinel lymph node biopsy (SLNB) in clinically node-negative (cN0) patients is currently questioned. Our objective was to investigate the cost-effectiveness of a preoperative noninvasive lymph no...
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Article
Open AccessPredicting pathological axillary lymph node status with ultrasound following neoadjuvant therapy for breast cancer
High-performing imaging and predictive markers are warranted to minimize surgical overtreatment of the axilla in breast cancer (BC) patients receiving neoadjuvant chemotherapy (NACT). Here we have investigated...
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Article
Open AccessMammographic density as an image-based biomarker of therapy response in neoadjuvant-treated breast cancer patients
Personalized cancer treatment requires predictive biomarkers, including image-based biomarkers. Breast cancer (BC) patients receiving neoadjuvant chemotherapy (NACT) are in a clinically vulnerable situation wi...
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Article
Open AccessMammographic density is a potential predictive marker of pathological response after neoadjuvant chemotherapy in breast cancer
Our aim is to study if mammographic density (MD) prior to neoadjuvant chemotherapy is a predictive factor in accomplishing a pathological complete response (pCR) in neoadjuvant-treated breast cancer patients.
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Article
Open AccessEffects of statin use on volumetric mammographic density: results from the KARMA study
Epidemiological data on statins and breast cancer risk have been inconclusive. The aim of this study was to clarify the role of statins in breast cancer risk by studying their effect on mammographic density.
