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Article
Upper airway stimulation for obstructive sleep apnea—Can radiological position monitoring predict tongue motion one year after implantation?
Tongue motion patterns (TMP) can influence the outcome of upper airway stimulation (UAS) in the treatment of obstructive sleep apnea (OSA). As a postoperative control, the cuff position of the stimulation lead...
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Article
Combined-modality 125J-seed-brachytherapy, external beam radiation and androgen deprivation therapy of unfavorable-risk prostate cancer: report of outcomes and side-effects
To analyze outcomes and complication rates in an unselected cohort of men with unfavorable (NCCN intermediate and high-risk) PCa receiving combined-modality radiation treatment (CRT).
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Article
Die obere Atemwegsstimulation bei obstruktiver Schlafapnoe – Kann die radiologische Lage des Stimulation-Cuff die Zungenbewegung vorhersagen?
Zungenbewegungsmuster (ZBM) können die Ergebnisse der oberen Atemwegsstimulation (UAS) bei der Behandlung der obstruktiven Schlafapnoe (OSA) beeinflussen. Üblicherweise wird nach der Implantation eine Lagekont...
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Article
Rückenlage- und REM-Bezug bei obstruktiver Schlafapnoe. Kritische Modellbetrachtungen
Der bisherige Diskurs zum Rückenlage- und REM-Schlafbezug bei obstruktiver Schlafapnoe (OSA) übernimmt die tradierte Festlegung eines mindestens doppelt so hohen Schweregrads in der entsprechenden Körperlage b...
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Article
Supine position and REM dependence in obstructive sleep apnea
When considering supine position and REM dependence, many studies refer to the traditional definition in which obstructive sleep apnea (OSA) severity is at least doubled in the corresponding position/sleep sta...
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Article
Pregnancy risk factors for very premature delivery: what role do hypertension, obesity and diabetes play?
Very premature delivery is a major cause of infant morbidity and mortality. Obesity, diabetes and pregnancy hypertension are known risk factors for pregnancy complications. The study aimed to scrutinize differ...
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Article
Distal and proximal interleukin (IL)-10 promoter polymorphisms associated with risk of cutaneous melanoma development: a case–control study
Inherited promoter polymorphisms of the interleukin (IL)-10 gene resulting in altered IL-10 production may contribute to a genetic susceptibility for melanoma. We investigated the role of a haplotype from distal ...
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Article
Predicting recovery after intracerebral hemorrhage – An external validation in patients from controlled clinical trials
An early and reliable prognostic indication in stroke patients is potentially useful for initiation of individual treatment and for informing patients and relatives. We recently developed a regression model as...
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Article
Erratum: Association of polymorphisms in the mannose-binding lectin gene and pulmonary morbidity in preterm infants
Correction to: Genes and Immunity (2007) 8, 671–677; doi:10.1038/sj.gene.6364432 Since publication of this paper, the authors have noticed that Table 1 is incorrect. The correct table is displayed below. The a...
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Article
Association of polymorphisms in the mannose-binding lectin gene and pulmonary morbidity in preterm infants
Deficiency in the collectin mannose-binding lectin (MBL) increases the risk for pulmonary and systemic infections and its complications in children and adults. The aim of this prospective cohort study was to d...
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Chapter and Conference Paper
Assoziation von regulatorischen Varianten des RET-Protoonkogens mit dem Morbus Hirschsprung (HSCR)
Hirschsprung disease (HSCR, MIM # 142623) is a complex congenital disorder of the enteric nervous system characterized by intestinal obstruction due to the absence of ganglion cells. Loss-of-function germline ...
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Article
Linkage analyses of chromosomal region 18p11-q12 in dyslexia
Dyslexia is characterized as a significant impairment in reading and spelling ability that cannot be explained by low intelligence, low school attendance or deficits in sensory acuity. It is known to be a here...
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Chapter and Conference Paper
Die Kombination von PHOX2B-Keimbahnmutationen mit spezifischen Haplotypen des RET-Protoonkogens ist assoziiert mit dem kombinierten Phänotyp aus kongenitalem zentralen Hypoventilationssyndrom und Morbus Hirschsprung
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Chapter and Conference Paper
Assoziation funktioneller Haplotypen des RET-Protoonkogen-Promotors mit dem Morbus Hirschsprung
The activation of the RET signaling pathway during embryogenesis is a crucial prerequisite for a directional migration of enteric nervous system progenitor cells. Loss-of-function germline mutations of the RET pr...
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Chapter
Symposia
Goal: The goal of this symposium is to identify ‘state-of-the-art’ strategies for the use of antipsychotic medications in the management of children and adolescents with major psychiatric disorders. Learning o...
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Article
Novel genetic variation of human interleukin-21 receptor is associated with elevated IgE levels in females
The interleukin-21 receptor (IL21R) was recently discovered as a novel member of the class-I-cytokine-receptor family and is selectively expressed in lymphoid tissues. IL21R shows strong sequence homologies to...
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Article
Spectrum of binge eating symptomatology in patients treated with clozapine and olanzapine
The authors explored the binge eating symptomatology in 74 patients receiving clozapine (N = 57) or olanzapine (N = 17), and compared body mass index (BMI, kg/m2) and weight gain in patients with and without bin...
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Chapter and Conference Paper
Statistical Genetics — Present and Future
One major task of statistical genetics is the development of efficient methods to identify disease predisposing genes. While genetic map** and positional cloning of Mendelian disorders can be considered rout...
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Article
Extrakorporale Stoßwellentherapie (ESWT) bei Epicondylitis humeri radialis
Dieser Übersichtsartikel bewertet Therapiemodalitäten und klinische Ergebnisse der extrakorporalen Stoßwellentherapie (ESWT) bei Epicondylitis humeri radialis (EHR) auf der Basis einer systematischen Literatur...
