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    Article

    Genetic risk score predicting accelerated progression from mild cognitive impairment to Alzheimer’s disease

    Aside from APOE, the genetic factors that influence the progression from mild cognitive impairment (MCI) to Alzheimer’s disease (AD) remain largely unknown. We assessed whether a genetic risk score (GRS), based o...

    E. Rodríguez-Rodríguez, P. Sánchez-Juan in Journal of Neural Transmission (2013)

  2. Article

    Erratum: Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

    Correction to: Molecular Psychiatry advance online publication, 20 March 2012; doi: 10.1038/mp.2012.14 Following the online publication of this article, the authors noted an error in Dr Caffarra's name. The co...

    J-C Lambert, B Grenier-Boley, D Harold, D Zelenika, V Chouraki in Molecular Psychiatry (2013)

  3. Article

    Open Access

    Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

    Recently, several genome-wide association studies (GWASs) have led to the discovery of nine new loci of genetic susceptibility in Alzheimer's disease (AD). However, the landscape of the AD genetic susceptibili...

    J-C Lambert, B Grenier-Boley, D Harold, D Zelenika, V Chouraki in Molecular Psychiatry (2013)

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    Article

    Carbon isotopes in otolith amino acids identify residency of juvenile snapper (Family: Lutjanidae) in coastal nurseries

    This study explored the potential for otolith geochemistry in snapper (Family: Lutjanidae) to identify residency in juvenile nursery habitats with distinctive carbon isotope values. Conventional bulk otolith a...

    K. W. McMahon, M. L. Berumen, I. Mateo, T. S. Elsdon, S. R. Thorrold in Coral Reefs (2011)

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    Article

    APOE and Alzheimer disease: a major gene with semi-dominant inheritance

    Apolipoprotein E (APOE) dependent lifetime risks (LTRs) for Alzheimer Disease (AD) are currently not accurately known and odds ratios alone are insufficient to assess these risks. We calculated AD LTR in 7351 cas...

    E Genin, D Hannequin, D Wallon, K Sleegers, M Hiltunen, O Combarros in Molecular Psychiatry (2011)

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    Article

    Aromatase and interleukin-10 genetic variants interactively modulate Alzheimer’s disease risk

    A chronic inflammatory process with activation of microglial cells contribute to the neurodegeneration associated with Alzheimer’s disease (AD). Estrogen could protect the brain from neurodegeneration by augme...

    O. Combarros, P. Sánchez-Juan, J. A. Riancho, I. Mateo in Journal of Neural Transmission (2008)

  7. No Access

    Article

    Genetic interaction between two apolipoprotein E receptors increases Alzheimer's disease risk

    E. Rodríguez, I. Mateo, J. Llorca, C. Sánchez–Quintana, J. Infante in Journal of Neurology (2006)

  8. No Access

    Article

    Cholesteryl ester transfer protein (CETP) polymorphism modifies the Alzheimer's disease risk associated with APOE ε4 allele

    Cholesterol regulates the production of amyloid beta (Aβ), which is central to the pathogenesis of Alzheimer's disease (AD), with high cellular cholesterol promoting and low cellular cholesterol reducing Aβ in...

    E. Rodríguez, I. Mateo, J. Infante, J. Llorca, J. Berciano in Journal of Neurology (2006)

  9. No Access

    Article

    The chemoattraction of lymphocytes by rheumatoid arthritis – synovial fluid is not dependent on the chemokine receptor CCR5

    The objective was to study the potential role of the chemokine receptor CCR5 in the chemoattraction of lymphocytes by rheumatoid arthritis synovial fluid (RA-SF).

    B. Santiago, M. Galindo, M. Rivero, M. Brehmer, I. Mateo in Rheumatology International (2002)

  10. Article

    Acute/Chronic respiratory failure III

    E. Fernàndez Mondèjar, G. Vazquez Mata, F. Ferròn, P. Navarrete in Intensive Care Medicine (1992)

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    Article

    Antibodies to extractable cellular antigens in Spanish systemic lupus erythematosus (SLE) patients

    We studied the frequency of antibodies to extractable cellular antigens in 90 Spanish SLE patients. Antibodies to Sm, nRNP, Ro and La were found, respectively, in 6 (6.6%), 18 (20%), 30 (33.3%) and 6 (6.6%) pa...

    P. E. Carreira, I. Mateo, G. Garcia, G. Garrido in Clinical Rheumatology (1987)