-
Article
Erratum: Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent
Correction to: Gene Therapy (2007) 14, 1175–1180; doi:10.1038/sj.gt.3302964 Since the above publication the authors have noticed that they unfortunately missed a grant support. The work was also supported by S...
-
Article
Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent
The development of new treatments in the post-genomic era requires methods for safe delivery of foreign genetic information in vivo. As a transient, natural and controllable alternative to recombinant viruses or ...
-
Article
Human peripheral blood monuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro
The efficiency of test vaccines needs to be evaluated by quantification of the triggered cellular immune response. Usually, for these assays, autologous target cells expressing the vaccine antigen are required...
-
Article
Polarization of immunity induced by direct injection of naked sequence-stabilized mRNA vaccines
In the context of develo** a safe genetic vaccination strategy we tested and studied globin-stabilized mRNA-based vaccination in mice. This vaccination strategy has the advantages of genetic vaccination (ea...