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    Low Molecular Weight NGF Mimetic Enhances the Overall Plasma Antioxidant Capacity in Rats with Streptozotocin-Induced Diabetes

    Results from studies of the antidiabetic and antihyperglycemic activity of a low-molecular-weight NGF mimetic, compound GR-2 [bis-(N-monosuccinyl-L-glutamyl-L-lysine)hexamethylenediamide], on a streptozotocin-ind...

    S. V. Ivanov, R. U. Ostrovskaya, V. V. Olicheva in Pharmaceutical Chemistry Journal (2024)

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    Development and Validation of a Method for Simultaneous Quantification of Dihydroquercetin and Secoisolariciresinol

    A method for simultaneous quantitative analysis of dihydroquercetin and secoisolariciresinol using HPLC with a diode-array detector (DAD) was developed, validated, and used for quantitative determination of th...

    K. S. Voronin, A. A. Fenin, A. K. Zhevlakova in Pharmaceutical Chemistry Journal (2023)

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    Polyphenolic Profile of Larch Knotwood

    Studies of the polyphenol profile of knotwood from larch Larix dahurica Turcz. by HPLC-DAD/ESI-MS/MS found that knotwood differed from the butt-log portion by the presence of a lignan fraction. The major constitu...

    K. S. Voronin, A. A. Fenin, A. K. Zhevlakova in Pharmaceutical Chemistry Journal (2021)

  4. Article

    Comparative Study of Wound-Healing Activity of Dihydroquercetin Pseudopolymorphic Modifications

    Wound-healing activity of the crystalline form of dihydroquercetin and its microtubular pseudopolymorphic modification obtained by crystal engineering was compared using the rat model of IIIA degree burn. The ...

    R. P. Terekhov, I. A. Selivanova in Bulletin of Experimental Biology and Medic… (2021)

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    Engineering of Dihydroquercetin Crystals

    Dihydroquercetin (DHQ) is a commercially available bioflavonoid with a wide range of pharmacological activity. The low water solubility at room temperature of the commercial drug substance limits development o...

    I. A. Selivanova, R. P. Terekhov in Pharmaceutical Chemistry Journal (2020)

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    Crystal engineering as a scientific basis for modification of physicochemical properties of bioflavonoids

    Flavonoids are of interest for pharmacy and medicinal chemistry due to a wide range of biological activities. The major goal for the design of new drugs based on flavonoids is to increase bioavailability of ph...

    I. A. Selivanova, R. P. Terekhov in Russian Chemical Bulletin (2019)

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    Some problems of the teaching of organic chemistry in universities of Russia

    I. P. Beletskaya, N. V. Lukashev, S. Z. Vatsadze in Russian Journal of Organic Chemistry (2017)

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    Study of the crystalline structure of dihydroquercetin

    I. A. Selivanova, N. A. Tyukavkina, Yu. A. Kolesnik in Pharmaceutical Chemistry Journal (1999)