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Article
Low Molecular Weight NGF Mimetic Enhances the Overall Plasma Antioxidant Capacity in Rats with Streptozotocin-Induced Diabetes
Results from studies of the antidiabetic and antihyperglycemic activity of a low-molecular-weight NGF mimetic, compound GR-2 [bis-(N-monosuccinyl-L-glutamyl-L-lysine)hexamethylenediamide], on a streptozotocin-ind...
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Article
Development and Validation of a Method for Simultaneous Quantification of Dihydroquercetin and Secoisolariciresinol
A method for simultaneous quantitative analysis of dihydroquercetin and secoisolariciresinol using HPLC with a diode-array detector (DAD) was developed, validated, and used for quantitative determination of th...
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Article
Polyphenolic Profile of Larch Knotwood
Studies of the polyphenol profile of knotwood from larch Larix dahurica Turcz. by HPLC-DAD/ESI-MS/MS found that knotwood differed from the butt-log portion by the presence of a lignan fraction. The major constitu...
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Article
Comparative Study of Wound-Healing Activity of Dihydroquercetin Pseudopolymorphic Modifications
Wound-healing activity of the crystalline form of dihydroquercetin and its microtubular pseudopolymorphic modification obtained by crystal engineering was compared using the rat model of IIIA degree burn. The ...
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Article
Engineering of Dihydroquercetin Crystals
Dihydroquercetin (DHQ) is a commercially available bioflavonoid with a wide range of pharmacological activity. The low water solubility at room temperature of the commercial drug substance limits development o...
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Article
Crystal engineering as a scientific basis for modification of physicochemical properties of bioflavonoids
Flavonoids are of interest for pharmacy and medicinal chemistry due to a wide range of biological activities. The major goal for the design of new drugs based on flavonoids is to increase bioavailability of ph...
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Article
Some problems of the teaching of organic chemistry in universities of Russia
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Article
Study of the crystalline structure of dihydroquercetin