-
Article
Clinical impact of hyperattenuation of adrenal glands on contrast-enhanced computed tomography of polytraumatised patients
To evaluate the prognostic value of hyperattenuating adrenal glands on contrast-enhanced CT of polytraumatised patients.
-
Article
PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death
To achieve malignancy, cancer cells convert numerous signaling pathways, with evasion from cell death being a characteristic hallmark. The cell death machinery represents an anti-cancer target demanding consta...
-
Article
Verlegungsrealität schwerverletzter Patienten in Deutschland
Drei Jahre nach Gründung des TraumaNetzwerkD DGU sind im Jahre 2009 ein Großteil der in Deutschland an der Schwerverletztenversorgung beteiligten Kliniken registriert und in regionalen Traumanetzwerken (TNW) orga...
-
Article
Open AccessBeyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells
Major contributors to atherosclerosis are oxidative damage and endoplasmic reticulum (ER) stress-induced apoptosis; both of which can be diminished by the anti-oxidative protein paraoxonase-2 (PON2). ER stress...
-
Article
Abbruch der Schockraumdiagnostik und Notfalloperation beim Polytrauma – Inzidenz und klinische Relevanz
Die Entscheidung zur Unterbrechung der Schockraumdiagnostik bei schwerverletzten Patienten aufgrund vital bedrohlicher Zustände mit der Notwendigkeit eines sofortigen operativen Eingriffs stellt eine außerorde...
-
Chapter and Conference Paper
Poster
Increasing ethical, commercial and scientific needs as well as public pressure have initiated worldwide activities to elaborate reliable in vitro alternatives to animal toxicity testing procedures. In the last tw...
-
Article
Comparison of the cytotoxicity and DNA-damaging properties of 2,4-D and U 46 D Fluid (dimethylammonium salt of 2,4-D)
U 46 D Fluid (the dimethylammonium salt of 2,4-dichlorophenoxyacetic acid in a commercial formulation) was more toxic to human fibroblasts than 2,4-dichlorophenoxyacetic acid (2,4-D). Moreover, U 46 D Fluid in...
-
Article
Metabolism of pentachlorophenol to tetrachlorohydroquinone by human liver homogenate
-
Article
Correlation of the colony-forming abilities of xeroderma pigmentosum fibroblasts with repair-specific DNA incision reactions catalyzed by cell-free extracts
Several normal and XP group A fibroblast cell lines were exposed to the weakly carcinogenic and toxic agent methyl methanesulfonate, and the differences in their abilities to form colonies were determined. The...
-
Article
On the biochemical mechanism of tumorigenesis in mouse skin
Mice were treated on their back skin with a single promoting dose of the tritium labelled phorbol ester A 1 (TPA-20-3H) in the standard manner. Methods were investigated for determination of the fate and distribu...
-
Chapter
On the Biochemical Mechanism of Tumorigenesis in Mouse Skin
Mice were treated on their back skin with a single promoting dose of the tritium labelled phorbol ester A l (TPA-20-3H) in the standard manner Methods were investigated for determination of the fate a...