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  1. No Access

    Article

    The nucleotide excision repair protein XPC is essential for bulky DNA adducts to promote interleukin-6 expression via the activation of p38-SAPK

    Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants, and many are potent carcinogens. Benzo[a]pyrene (B[a]P), one of the best-studied PAHs, is metabolized ultimately to the genotoxin anti-B[a]P-7...

    I Schreck, N Grico, I Hansjosten, C Marquardt, S Bormann, A Seidel… in Oncogene (2016)

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    Article

    TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A

    The aryl hydrocarbon receptor (AhR) is a transcription factor involved in physiological processes, but also mediates most, if not all, toxic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Activation of ...

    C Weiss, D Faust, I Schreck, A Ruff, T Farwerck, A Melenberg, S Schneider… in Oncogene (2008)