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    The FEN1 E359K germline mutation disrupts the FEN1–WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers

    Polymorphisms and somatic mutations in Flap Endonuclease 1 (FEN1), an essential enzyme involved in DNA replication and repair, can lead to functional deficiencies of the FEN1 protein and a predisposition to ca...

    L Chung, D Onyango, Z Guo, P Jia, H Dai, S Liu, M Zhou, W Lin, I Pang, H Li… in Oncogene (2015)