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Article
Open AccessTAP2, a peptide antagonist of Toll-like receptor 4, attenuates pain and cartilage degradation in a monoiodoacetate-induced arthritis rat model
Because inflammation in osteoarthritis (OA) is related to the Toll-like receptor 4 (TLR4) signaling cascades, TLR4 is a reasonable target for develo** therapeutics for OA. Thus, we investigated whether TAP2,...
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Article
Open AccessLoss of Ewing sarcoma EWS allele promotes tumorigenesis by inducing chromosomal instability in zebrafish
The Ewing sarcoma family of tumors expresses aberrant EWSR1- (EWS) fusion genes that are derived from chromosomal translocation. Although these fusion genes are well characterized as transcription factors, their ...