Skip to main content

2 Result(s)

within Hyewon Park Remove this filter Neurology Remove this filter

and

  1. Article

    Open Access

    Rejuvenating aged microglia by p16ink4a-siRNA-loaded nanoparticles increases amyloid-β clearance in animal models of Alzheimer’s disease

    Age-dependent accumulation of amyloid plaques in patients with sporadic Alzheimer’s disease (AD) is associated with reduced amyloid clearance. Older microglia have a reduced ability to phagocytose amyloid, so ...

    Hyo Jung Shin, In Soo Kim, Seung Gyu Choi, Kayoung Lee… in Molecular Neurodegeneration (2024)

    Download PDF (9145 KB) View Article

  2. No Access

    Article

    Protective Effects of ShcA Protein Silencing for Photothrombotic Cerebral Infarction

    Reactive oxygen species (ROS) exacerbate stroke-induced cell damage. We found that ShcA, a protein that regulates ROS, is highly expressed in a Rose Bengal photothrombosis model. We investigated whether ShcA i...

    Jeong-Ah Hwang, Nara Shin, Hyo Jung Shin, Yuhua Yin… in Translational Stroke Research (2021)