-
Article
Open AccessNIR triggered polydopamine coated cerium dioxide nanozyme for ameliorating acute lung injury via enhanced ROS scavenging
Acute lung injury (ALI) is a life threatening disease in critically ill patients, and characterized by excessive reactive oxygen species (ROS) and inflammatory factors levels in the lung. Multiple evidences su...
-
Article
Ti–Zr–Cu–Co–Fe amorphous/nanocrystalline brazing filler metals for joining Ti-6Al-4V alloy
A novel Ti50Zr30Cu8Co7Fe5 (at.%) amorphous/nanocrystalline brazing filler metal (BFM) with low Cu content and low liquidus temperature (1154 K) was developed and prepared into a flexible ribbon by melt-spinning f...
-
Article
Open AccessElevated ADH5 expression suggested better prognosis in kidney renal clear cell carcinoma (KIRC) and related to immunity through single-cell and bulk RNA-sequencing
Despite the rapid advances in modern medical technology, kidney renal clear cell carcinoma (KIRC) remains a challenging clinical problem in urology. Researchers urgently search for useful markers to break thro...
-
Article
Appropriate control measure design by rapidly identifying risk areas of volatile organic compounds during the remediation excavation at an organic contaminated site
Many organic contaminated sites require on-site remediation; excavation remediation processes can release many volatile organic compounds (VOCs) which are key atmospheric pollutants. It is therefore important ...
-
Article
Open AccessPerinatal mental health services for women from minority ethnic groups: why patient-centred approach matter
-
Article
A reinforcement learning-based optimal control approach for managing an elective surgery backlog after pandemic disruption
Contagious disease pandemics, such as COVID-19, can cause hospitals around the world to delay nonemergent elective surgeries, which results in a large surgery backlog. To develop an operational solution for pr...
-
Article
Open AccessMagnesium-alloy rods reinforced bioglass bone cement composite scaffolds with cortical bone-matching mechanical properties and excellent osteoconductivity for load-bearing bone in vivo regeneration
Various therapeutic platforms have been developed for repairing bone defects. However, scaffolds possess both cortical bone-matching mechanical properties and excellent osteoconductivity for load-bearing bone ...
-
Article
Hydroxyapatite scaffolds containing copper for bone tissue engineering
The current study involves fabrication and characterization of HA scaffolds containing different copper (Cu) content by ion exchange and 3D extrusion deposition technique. The fabricated pure HA and Cu-doped s...
-
Article
Biofunctionalized self-assembly of peptide amphiphile induces the differentiation of bone marrow mesenchymal stem cells into neural cells
Bone marrow mesenchymal stem cells (BMSCs) are multipotential differentiation cells which can differentiate into different cell types such as osteoblasts, chondrocytes, adipocytes, cardiomyocytes, hepatocytes,...
-
Article
Open AccessB4GALT1 expression predicts prognosis and adjuvant chemotherapy benefits in muscle-invasive bladder cancer patients
The expression alterations of B4GALT1 have been noted in some types of cancer and they are related to cancer cell proliferation, invasiveness, metastasis, and drug resistance. We aimed to establish the express...
-
Article
Open AccessAuthor Correction: The Oncogenic Role of COL23A1 in Clear Cell Renal Cell Carcinoma
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
-
Article
Prognostic and Predictive Value of O6-methylguanine Methyltransferase for Chemotherapy in Patients with Muscle-Invasive Bladder Cancer
DNA repair genes are potential biomarkers for chemotherapy in muscle-invasive bladder cancer (MIBC). O6-methylguanine methyltransferase (MGMT) is involved in DNA repair and is found to affect the efficacy of plat...
-
Article
Open AccessThe Oncogenic Role of COL23A1 in Clear Cell Renal Cell Carcinoma
Clear cell renal cell carcinoma (ccRCC) is the most common adult renal neoplasm and its incidence continues to increase. Collagen is the most abundant extracellular matrix protein in stroma, and contributes to...
-
Article
Open AccessStrengthening health system to improve immunization for migrants in China
Immunization is the most cost-effective method to prevent and control vaccine-preventable diseases. Migrant population in China has been rising rapidly, and their immunization status is poor. China has tried v...
-
Article
Tumor Infiltrating Mast Cells (TIMs) Confers a Marked Survival Advantage in Nonmetastatic Clear-Cell Renal Cell Carcinoma
The role played by the innate immune system in determining the clinical outcome of clear-cell renal cell carcinoma (ccRCC) was still blurred. This study was designed to investigate the prognostic significance ...
-
Article
Open AccessFinancing strategies to improve essential public health equalization and its effects in China
In 2009, China launched a health reform to promote the equalization of national essential public health services package (NEPHSP). The present study aimed to describe the financing strategies and mechanisms to...
-
Article
Increased expression of interleukin-8 is an independent indicator of poor prognosis in clear-cell renal cell carcinoma
On the basis of aberrant interleukin-8 (IL-8) expression, a crucial angiogenesis factor and potential therapeutic target, in clear-cell renal cell carcinoma (ccRCC), this study aims to assess the prognostic si...
-
Article
Clinically Applicable Self-Healing Dental Resin Composites
Self-healing is one of the most desired material properties. Herein, we present the design and development of a new self-healing dental composite (SHDC) that can heal micro-cracks autonomously. The SHDC has tw...
-
Article
A unique solution for principal component analysis-based multi-response optimization problems
A procedure to find a unique solution for multi-response optimization problems based on indexing is presented. The procedure utilizes principal component analysis to map the original data to a new vector of co...
-
Article
Open AccessRoom temperature sol-gel fabrication and functionalization for sensor applications
The structure and physical properties of a thin titania sol-gel layer prepared on silicon and silica surfaces were examined. Spectroscopic (FTIR, UV-VIS spectroscopy), refractive index (ellipsometry) and micro...