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Article
Open AccessSoil organic carbon stocks increased across the tide-induced salinity transect in restored mangrove region
Blue carbon in mangrove ecosystems contributes significantly to the global carbon cycle. However, large uncertainties maintain in the soil organic carbon (SOC) storage throughout the tide-induced salinity and ...
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Article
Fine classification of rice paddy using multitemporal compact polarimetric SAR C band data based on machine learning methods
Rice is an important food crop for human beings. Accurately distinguishing different varieties and sowing methods of rice on a large scale can provide more accurate information for rice growth monitoring, yiel...
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Article
Open AccessLong-Term Cost-Effectiveness Analysis of Once-Weekly Semaglutide versus Dulaglutide in Patients with Type 2 Diabetes with Inadequate Glycemic Control in China
The objective of the current study was to assess the long-term cost-effectiveness of once-weekly semaglutide 0.5 mg and 1.0 mg versus dulaglutide 1.5 mg for the treatment of patients with type 2 diabetes uncon...
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Article
Open AccessEfficacy and safety of monotherapy and combination therapy of immune checkpoint inhibitors as first-line treatment for unresectable hepatocellular carcinoma: a systematic review, meta-analysis and network meta-analysis
Hepatocellular carcinoma (HCC) is one of the cancers with the highest morbidity and mortality. Sorafenib used to be the main treatment for unresectable HCC patients. However, regimens based on immune checkpoin...
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Article
Epidemiology and disease burden of non-alcoholic steatohepatitis in greater China: a systematic review
Non-alcoholic steatohepatitis (NASH) is a progression of non-alcoholic fatty liver disease. The increasing burden of NASH has become a major concern of public health in greater China. This study aimed to chara...
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Article
Open AccessDichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway
The development of chemoresistance remains a major challenge that accounts for colorectal cancer (CRC) lethality. Dichloroacetate (DCA) was originally used as a metabolic regulator in the treatment of metaboli...