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  1. Article

    Open Access

    Anti-CD166/4-1BB chimeric antigen receptor T cell therapy for the treatment of osteosarcoma

    Chimeric antigen receptor (CAR)-engineered T cells have displayed outstanding performance in the treatment of patients with hematological malignancies. However, their efficacy against solid tumors has been lar...

    Yitian Wang, Wei Yu, Jian Zhu, Junjie Wang in Journal of Experimental & Clinical Cancer … (2019)

  2. Article

    Open Access

    mTORC1 accelerates osteosarcoma progression via m6A-dependent stabilization of USP7 mRNA

    Osteosarcoma (OS) is considered a sex steroid hormone-dependent bone tumor. The development and progression of OS are regulated by 17β-estradiol (E2). However, the detailed mechanisms of E2-modulated OS progre...

    Zhengming Yang, Wei Yu, Ankai Xu, Bing Liu, Libin **, Huimin Tao in Cell Death Discovery (2024)