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Article
5-hydroxytryptamine 2C/1A receptors modulate the biphasic dose response of the head twitch response and locomotor activity induced by DOM in mice
The phenylalkylamine hallucinogen (-)-2,5-dimethoxy-4-methylamphetamine (DOM) exhibits an inverted U-shaped dose-response curve for both head twitch response (HTR) and locomotor activity in mice. Accumulated s...
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Article
Open AccessEffects and long-term outcomes of endurance versus resistance training as an adjunct to standard medication in patients with stable COPD: a multicenter randomized trial
Comparisons between endurance training (ET) and resistance training (RT) have produced equivocal findings in chronic obstructive pulmonary disease (COPD) patients. The purpose of our study is to investigate th...
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Article
Open AccessAuthor Correction: Insights and implications of sexual dimorphism in osteoporosis
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Open AccessInsights and implications of sexual dimorphism in osteoporosis
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures worldwide. Accumulating evid...
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Article
Open AccessCHCHD2 up-regulation in Huntington disease mediates a compensatory protective response against oxidative stress
Huntington disease (HD) is a neurodegenerative disease caused by the abnormal expansion of a polyglutamine tract resulting from a mutation in the HTT gene. Oxidative stress has been identified as a significant co...
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Article
Open AccessStress hyperglycemia increases short-term mortality in acute ischemic stroke patients after mechanical thrombectomy
Glucose-to-glycated hemoglobin ratio (GAR) is considered a more reliable marker of stress hyperglycemia by correcting for basal blood glucose levels. This study aimed to investigate the extent to which GAR is ...
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Article
Increased Expression of TGF-β1 Contributes to the Downregulation of Progesterone Receptor Expression in the Eutopic Endometrium of Infertile Women with Minimal/Mild Endometriosis
Endometriosis is a hormone-dependent disease associated with impaired immunoregulation. In our recent study, we have characterized the trascriptomic transformation of eutopic endometrium from patients with min...
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Article
Open AccessSarcopenia negatively affects postoperative short-term outcomes of patients with non-cirrhosis liver cancer
Literature review have shown that sarcopenia substantially alters the postoperative outcomes after liver resection for malignant tumors. However, these retrospective studies do not distinguish cirrhotic and no...
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Therapy for Metastatic Pancreatic Cancer
In this chapter, we provide a chronologic overview of the treatment of metastatic pancreatic ductal adenocarcinoma. We begin by enumerating landmark trials that established systemic chemotherapy as the current...
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Article
Correction to: Comparative Proteomic Analysis Reveals Metformin Improves the Expression of Biomarkers of Endometrial Receptivity in Infertile Women with Minimal/Mild Endometriosis
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Article
Energy band alignment of 2D/3D MoS2/4H-SiC heterostructure modulated by multiple interfacial interactions
The interfacial properties of MoS2/4H-SiC heterostructures were studied by combining first-principles calculations and X-ray photoelectron spectroscopy. Experimental (theoretical) valence band offsets (VBOs) incr...
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Article
Comparative Proteomic Analysis Reveals Metformin Improves the Expression of Biomarkers of Endometrial Receptivity in Infertile Women with Minimal/Mild Endometriosis
The prevalence of endometriosis is approximately 10% in women of reproductive age, and 30–50% of women with endometriosis are infertile. Metformin has been reported to inhibit the growth of ectopic lesions in ...
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Article
Interfacial properties of 2D WS2 on SiO2 substrate from X-ray photoelectron spectroscopy and first-principles calculations
Two-dimensional (2D) WS2 films were deposited on SiO2 wafers, and the related interfacial properties were investigated by high-resolution X-ray photoelectron spectroscopy (XPS) and first-principles calculations. ...
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Article
Open AccessInnate lymphoid cells exhibited IL-17-expressing phenotype in active tuberculosis disease
Innate lymphoid cells (ILCs), as an important group of innate immunity, could respond rapidly to Mycobacterium tuberculosis (Mtb) infection. In this research, we studied the phenotypic changes of circulatory ILCs...
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Article
Open AccessGrowth hormone activates PI3K/Akt signaling and inhibits ROS accumulation and apoptosis in granulosa cells of patients with polycystic ovary syndrome
It is reported that growth hormone (GH) can alleviate oxidative stress (OS) induced apoptosis in some types of cells by activating the PI3K/Akt signaling pathway. This study investigated the role and underlyin...
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Open AccessGrowth hormone alleviates oxidative stress and improves oocyte quality in Chinese women with polycystic ovary syndrome: a randomized controlled trial
Oxidative stress (OS) is associated with poor oocyte quality and in vitro fertilization and embryo transfer (IVF-ET) outcomes for patients with polycystic ovary syndrome (PCOS). Growth hormone (GH) can functio...
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Article
Open AccessPancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target
Pancreatic ductal adenocarcinoma (PDAC) lethality is due to metastatic dissemination. Characterization of rare, heterogeneous circulating tumor cells (CTCs) can provide insight into metastasis and guide develo...
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Article
Occurrence of a Cryptosporidium xiaoi–like genotype in peafowl (Pavo cristatus) in China
The aim of this study was to survey the Cryptosporidium species in peafowls (Pavo cristatus) in Henan Province, China. A total of 143 fecal specimens collected from a breeding farm were tested for Cryptosporidium
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Body fat indices as effective predictors of insulin resistance in obese/non-obese polycystic ovary syndrome women in the Southwest of China
Insulin resistance (IR) is a common feature of polycystic ovary syndrome (PCOS). Body fat indices can be predictive markers of IR. This study is aimed to predict IR in Chinese women with PCOS of different body...
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Open AccessMicroRNA expression profile of HCT-8 cells in the early phase of Cryptosporidium parvum infection
Cryptosporidium parvum is an important zoonotic parasitic disease worldwide, but the molecular mechanisms of the host–parasite interaction are not fully understood. Noncoding microRNAs (miRNAs) are considered key...
