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Article
A symbiosis between Euploea butterflies and yeasts
Euploea butterflies harbor many yeast species on their mouthparts, legs, and wings. In this study, we focused on the distribution of two dominant yeast species, Candida corydali and Metschnikowia koreensis. We in...
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Article
Open AccessThe ESCRT-III molecules regulate the apical targeting of bile salt export pump
The bile salt export pump (BSEP) is a pivotal apical/canalicular bile salt transporter in hepatocytes that drives the bile flow. Defects in BSEP function and canalicular expression could lead to a spectrum of ...
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Article
Synthesis, Structure, Characterizations, Photocatalytic and Thermal Decomposition Properties of a Novel 2-Dimensional Sandwich-Type Phosphomolybdate
A novel 2-dimensional phosphomolybdate, (H3O)4{Zn2[Zn[H7Mo6VO15(PO4)4]2]} (1), which is a non-classical sandwich-type inorganic compound, has been synthesized and systematically characterized. As polyoxometalates...
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Article
Open AccessLiver Gene Expression Profiles Correlate with Virus Infection and Response to Interferon Therapy in Chronic Hepatitis B Patients
The natural course of chronic hepatitis B (CHB) infection and treatment response are determined mainly by the genomic characteristics of the individual. We investigated liver gene expression profiles to reveal...
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Article
Clinical significance of circulating miR-122 in patients with dual chronic hepatitis B and C virus infection
The clinical significance of serum microRNA-122 (miR-122) has been shown in viral hepatitis B and C, respectively. Specifically, miR-122 stimulates hepatitis C virus (HCV) replication but suppresses hepatitis...
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Article
Serum interleukin 6 level correlates with outcomes of acute exacerbation of chronic hepatitis B
Acute exacerbation (AE) of chronic hepatitis B virus (HBV) infection is common and negatively impacts the clinical outcome. Factors predicting outcomes after exacerbations were only partly clarified. We invest...
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Article
Open AccessStrategically examining the full-genome of dengue virus type 3 in clinical isolates reveals its mutation spectra
Previous studies presented the quasispecies spectrum of the envelope region of dengue virus type 3 (DENV-3) from either clinical specimens or field-caught mosquitoes. However, the extent of sequence variation ...
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Protocol
Induction of Humoral and Cellular Immune Responses to Hepatitis Delta Virus Through DNA Immunization in BALB/c Mice
“Current regimens (interferon) to treat hepatitis D patients have only transient but no lasting effects (1).”
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Article
Long-term culture of hepatocytes from human adults
A long-term primary human hepatocyte culture retraining liver-specific functions is important and essential for basic research and for the future development of hepatocyte-based applications. We established a ...
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Article
Inhibition of hepatitis delta virus genomic ribozyme self-cleavage by aminoglycosides
Subgenomic regions of hepatitis delta virus (HDV) RNA contains ribozyme whose activities are important to viral life cycles and depend on a unique pseudoknot structure. To explore the characters of HDV ribozym...
