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    Article

    Novel K6-K14 keratin fusion enhances cancer stemness and aggressiveness in oral squamous cell carcinoma

    Keratin intermediate filament (IF) is one component of cellular architectures, which provides necessary mechanical support to conquer environmental stresses. Recent findings reveal its involvement in mechano-t...

    Fuu-Jen Tsai, Ming-Tsung Lai, Jack Cheng, Stev Chun-Chin Chao in Oncogene (2019)

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    Open Access

    Antitumor properties of Coenzyme Q0 against human ovarian carcinoma cells via induction of ROS-mediated apoptosis and cytoprotective autophagy

    Coenzyme Q0 (CoQ0, 2,3-dimethoxy-5-methyl-1,4-benzoquinone) has been reported to exert anticancer properties against human breast/lung cancer cells. This study investigated the in vitro and in vivo anticancer pro...

    You-Cheng Hseu, Tai-Jung Tsai, Mallikarjuna Korivi, Jer-Yuh Liu in Scientific Reports (2017)

  3. Article

    Open Access

    Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling

    The bioflavonoid apigenin has been shown to possess cancer-preventive and anti-cancer activities. In a drug screening, we found that apigenin can inhibit Wnt/β-catenin signaling, a pathway that participates in...

    Chung-Ming Lin, Hsin-Han Chen, Chun-An Lin, Hui-Chung Wu in Scientific Reports (2017)

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    Article

    The identification, purification, and characterization of STXF10 expressed in Streptomyces thermonitrificans NTU-88

    Multiple xylanolytic enzymes of Streptomyces thermonitrificans NTU-88 were induced by oat-spelt xylan and separated by two-dimensional polyacrylamide and zymogram gels. Nineteen clear spots differed in pI and mol...

    Hsueh-Ling Cheng, Chih-Yun Tsai, Hui-Jye Chen in Applied Microbiology and Biotechnology (2009)