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Hui**g Chen
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Article
Open AccessPreventive Effects of Dental Pulp Stem Cell-conditioned Media on Anti-RANKL Antibody-Related Osteonecrosis of the Jaw
Medication-related osteonecrosis of the jaw is a serious disease occurring in patients with cancer and osteoporosis, who are undergoing treatment with antiresorptive agents (ARAs) such as bisphosphonate (BP) o...
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Open AccessCardiac adverse events associated with lacosamide: a disproportionality analysis of the FAERS database
Lacosamide was the first approved third-generation antiepileptic drug. However, real-world data regarding its adverse cardiac reactions in large samples still need to be completed. We evaluated the cardiac saf...
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Open AccessMultiparametric MRI–based radiomic models for early prediction of response to neoadjuvant systemic therapy in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is often treated with neoadjuvant systemic therapy (NAST). We investigated if radiomic models based on multiparametric Magnetic Resonance Imaging (MRI) obtained early durin...
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Open AccessSETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis
Ewing’s sarcoma (ES) represents a rare yet exceedingly aggressive neoplasm that poses a significant health risk to the pediatric and adolescent population. The clinical outcomes for individuals with relapsed o...
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Open AccessEnvironment random interaction of rime optimization with Nelder-Mead simplex for parameter estimation of photovoltaic models
As countries attach importance to environmental protection, clean energy has become a hot topic. Among them, solar energy, as one of the efficient and easily accessible clean energy sources, has received wides...
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Open AccessQuantitative transport map** of multi-delay arterial spin labeling MRI detects early blood perfusion alterations in Alzheimer’s disease
Quantitative transport map** (QTM) of blood velocity, based on the transport equation has been demonstrated higher accuracy and sensitivity of perfusion quantification than the traditional Kety’s method-base...
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Open AccessEffect of silicon spraying on rice photosynthesis and antioxidant defense system on cadmium accumulation
Cadmium (Cd) pollution is a serious threat to food safety and human health. Minimizing Cd uptake and enhancing Cd tolerance in plants are vital to improve crop yield and reduce hazardous effects to humans. In ...
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Open AccessMetformin modifies plasma microbial-derived extracellular vesicles in polycystic ovary syndrome with insulin resistance
This study investigated changes in plasma microbial-derived extracellular vesicles (EVs) in patients with polycystic ovary syndrome and insulin resistance (PCOS-IR) before and after metformin treatment, and ai...
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Open AccessCorrection: Making the Complicated Simple: A Minimizing Carrier Strategy on Innovative Nanopesticides
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Open AccessExome sequencing and genome-wide association analyses unveils the genetic predisposition in hydroxychloroquine retinopathy
To unveil the candidate susceptibility genes in chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy using whole exome sequencing (WES) and genome-wide association study (GWAS).
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Open AccessGadolinium-enhanced intracranial aneurysm wall imaging and risk of aneurysm growth and rupture: a multicentre longitudinal cohort study
In patients with an unruptured intracranial aneurysm, gadolinium enhancement of the aneurysm wall is associated with growth and rupture. However, most previous studies did not have a longitudinal design and di...
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Open AccessRole of arachidonic acid in ischemic heart disease under different comorbidities: risk or protection?
In a translational study involving animal models and human subjects, Lv et al. demonstrate that arachidonic acid (AA) exhibits cardioprotective effects in diabetic myocardial ischemia, suggesting a departure f...
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Open AccessDifferences in the depression and burnout networks between doctors and nurses: evidence from a network analysis
Previous studies have demonstrated a strong association between depression and job burnout among healthcare professionals, but the results have been inconsistent, and there is a lack of in-depth exploration of...
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Open AccessBurden of drug use disorders in the United States from 1990 to 2021 and its projection until 2035: results from the GBD study
Drug use disorders (DUDs) have emerged as one of the most significant public health crises, exerting a substantial influence on both community health and socio-economic progress. The United States (US) also su...
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Correction: Machine learning detects symptomatic patients with carotid plaques based on 6-type calcium configuration classification on CT angiography
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Open AccessThe performance of the practices associated with the occurrence of severe intraventricular hemorrhage in the very premature infants: data analysis from the Chinese neonatal network
The occurrence of severe intraventricular hemorrhage (sIVH) was high in the very preterm infants (VPIs) in China. The management strategies significantly contributed to the occurrence of sIVH in VPIs. However,...
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Open AccessNavel orange peel essential oil inhibits the growth and progression of triple negative breast cancer
Triple Negative Breast Cancer (TNBC) is a particular type of breast cancer with the highest mortality rate. Essential oils are concerned more and more as potential anti-cancer drugs.
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Open AccessAssociation of myosteatosis with short-term outcomes in patients with acute-on-chronic liver failure
Sarcopenia (low muscle mass, i.e., quantity) is associated with poor clinical outcomes in patients with acute-on-chronic liver failure (ACLF). In this study, we aimed to illustrate the clinical prognostic valu...
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Open AccessNotable dysthymia: evolving trends of major depressive disorders and dysthymia in China from 1990 to 2019, and projections until 2030
Depressive disorders have been identified as a significant contributor to non-fatal health loss in China. Among the various subtypes of depressive disorders, dysthymia is gaining attention due to its similarit...
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Open AccessImproved Latin hypercube sampling initialization-based whale optimization algorithm for COVID-19 X-ray multi-threshold image segmentation
Image segmentation techniques play a vital role in aiding COVID-19 diagnosis. Multi-threshold image segmentation methods are favored for their computational simplicity and operational efficiency. Existing thre...
