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  1. Article

    Open Access

    GLOSSI: a method to assess the association of genetic loci-sets with complex diseases

    The developments of high-throughput genoty** technologies, which enable the simultaneous genoty** of hundreds of thousands of single nucleotide polymorphisms (SNP) have the potential to increase the benefi...

    High-Seng Chai, Hugues Sicotte, Kent R Bailey, Stephen T Turner… in BMC Bioinformatics (2009)

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  2. Article

    Open Access

    SNPPicker: High quality tag SNP selection across multiple populations

    Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genoty** every single SNP. However, existing tag SNP selec...

    Hugues Sicotte, David N Rider, Gregory A Poland, Neelam Dhiman… in BMC Bioinformatics (2011)

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  3. Article

    Open Access

    MAP-RSeq: Mayo Analysis Pipeline for RNA sequencing

    Although the costs of next generation sequencing technology have decreased over the past years, there is still a lack of simple-to-use applications, for a comprehensive analysis of RNA sequencing data. There i...

    Krishna R Kalari, Asha A Nair, Jaysheel D Bhavsar, Daniel R O’Brien… in BMC Bioinformatics (2014)

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  4. Article

    Open Access

    Measure transcript integrity using RNA-seq data

    Stored biological samples with pathology information and medical records are invaluable resources for translational medical research. However, RNAs extracted from the archived clinical tissues are often substa...

    Liguo Wang, **fu Nie, Hugues Sicotte, Ying Li… in BMC Bioinformatics (2016)

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