58 Result(s)

Article

Unveiling biosynthetic potential of an Arctic marine-derived strain Aspergillus sydowii MNP-2

A growing number of studies have demonstrated that the polar regions have the potential to be a significant repository of microbial resources and a potential source of active ingredients. Genome mining strateg...

Zhiyang Fu, **angzhou Gong, Zhe Hu, Bin Wei, Huawei Zhang in BMC Genomics (2024)

Article

Metabolomics and proteomics insights into subacute ruminal acidosis etiology and inhibition of proliferation of yak rumen epithelial cells in vitro

Untargeted metabolomics and proteomics were employed to investigate the intracellular response of yak rumen epithelial cells (YRECs) to conditions mimicking subacute rumen acidosis (SARA) etiology, including e...

JunMei Wang, Liyuan Shi, **aohong Zhang, Rui Hu, Ziqi Yue, Huawei Zou… in BMC Genomics (2024)

Article

Correction: Transcriptomics and metabolomics of blood, urine and ovarian follicular fuid of yak at induced estrus stage

Huangqing Zhao, Yongzhen Huang, Shi Shu, Guowen Wang, Changqi Fu… in BMC Genomics (2024)

Article

Optimization of fermentation conditions and medium components for chrysomycin a production by Streptomyces sp. 891-B6

Chrysomycin A (CA) is a promising antibiotic for treatment of Gram-positive bacterial infections and cancers. In order to enhance CA yield, optimization of fermentation conditions and medium components was car...

Zhe Hu, Qiangang Weng, Zhehui Cai, Huawei Zhang in BMC Microbiology (2024)

Article

Transcriptomics and metabolomics of blood, urine and ovarian follicular fluid of yak at induced estrus stage

To gain a deeper understanding of the metabolic differences within and outside the body, as well as changes in transcription levels following estrus in yaks, we conducted transcriptome and metabolome analyses ...

Huangqing Zhao, Yongzhen Huang, Shi Shu, Guowen Wang, Changqi Fu… in BMC Genomics (2024)

Article

Response of rhizosphere soil physicochemical properties and microbial community structure to continuous cultivation of tobacco

The health of rhizosphere soil microorganisms is an important indicator to evaluate soil quality. Therefore, understanding the response of rhizosphere soil microorganisms to tobacco crop succession is crucial ...

Bo Gong, Yi He, Zhenbao Luo, Huawei Peng, Heqing Cai, Yuening Zhu… in Annals of Microbiology (2024)

Article

Author Correction: Redesigning the tomato fruit shape for mechanized production

Qiang Zhu, Lei Deng, Jie Chen, Gustavo R. Rodríguez, Chuanlong Sun… in Nature Plants (2024)

Article

Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model

Impaired pattern separation occurs in the early stage of Alzheimer’s disease (AD), and hippocampal dentate gyrus (DG) neurogenesis participates in pattern separation. Here, we investigated whether spatial memo...

Yanyi Ding, Long Li, Sinuo Wang, Yajun Cao, Minguang Yang… in Biological Research (2023)

Article

Time series single-cell transcriptional atlases reveal cell fate differentiation driven by light in Arabidopsis seedlings

Light serves as the energy source for plants as well as a signal for growth and development during their whole life cycle. Seedling de-etiolation is the most dramatic manifestation of light-regulated plant dev...

Xue Han, Yilin Zhang, Zhiying Lou, Jian Li, Zheng Wang, Chunlei Gao… in Nature Plants (2023)

Article

Genetic insights into the dissolution of dioecy in diploid persimmon Diospyros oleifera Cheng

Dioecy, a sexual system of single-sexual (gynoecious/androecious) individuals, is rare in flowering plants. This rarity may be a result of the frequent transition from dioecy into systems with co-sexual indivi...

Peng Sun, Soichiro Nishiyama, Huawei Li, Yini Mai, Weijuan Han… in BMC Plant Biology (2023)

Article

The impact of the gut microbiome on tumor immunotherapy: from mechanism to application strategies

Immunotherapy is one of the fastest develo** areas in the field of oncology. Many immunological treatment strategies for refractory tumors have been approved and marketed. Nevertheless, much clinical and pre...

Ciliang Guo, Lingkai Kong, Lingjun **ao, Kua Liu, Huawei Cui… in Cell & Bioscience (2023)

Article

Electroacupuncture protective effects after cerebral ischemia are mediated through miR-219a inhibition

Electroacupuncture (EA) is a complementary and alternative therapy which has shown protective effects on vascular cognitive impairment (VCI). However, the underlying mechanisms are not entirely understood.

Yaling Dai, Sinuo Wang, Minguang Yang, Peiyuan Zhuo, Yanyi Ding… in Biological Research (2023)

Article

A loop-mediated isothermal amplification assay for the rapid diagnosis of soybean rust caused by Phakopsora pachyrhizi

Soybean rust caused by the fungus Phakopsora pachyrhizi is one of the most destructive diseases to soybean production worldwide. For the rapid diagnosis and the control of soybean rust, we developed a loop-mediat...

Haibing Ouyang, Zhichao Zhang, Guangzheng Sun, Huawei Yang… in Phytopathology Research (2023)

Article

Plant growth regulators improve nitrogen metabolism, yield, and quality of soybean–rhizobia symbiosis

In recent years, considerable research has been conducted on the use of plant growth regulators (PGRs) to improve crop yields. Large amounts of PGRs are applied to regulate crop growth. However, few studies ha...

Wenhao Chen, Juan Li, Huawei Yuan, Ling You, Qin Wei… in Annals of Microbiology (2023)

Article

The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice

Mutations in GJB2 (Gap junction protein beta 2) are the most common genetic cause of non-syndromic hereditary deafness in humans, especially the 35delG and 235delC mutations. Owing to the homozygous lethality of

Qing Li, Chong Cui, Rongyu Liao, **di Yin… in Cellular and Molecular Life Sciences (2023)

Article

Polyketides with potential bioactivities from the mangrove-derived fungus Talaromyces sp. WHUF0362

Metabolites of microorganisms have long been considered as potential sources for drug discovery. In this study, five new depsidone derivatives, talaronins A-E (1–5) and three new xanthone derivatives, talaronins ...

Huawei Lv, Haibo Su, Yaxin Xue, Jia Jia, Hongkai Bi… in Marine Life Science & Technology (2023)

Article

The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model

The CRISPR-Cas13 system is an RNA-guided RNA-targeting system and has been widely used in transcriptome engineering with potentially important clinical applications. However, it is still controversial whether ...

Yunfei Li, Junjie Xu, Xuefei Guo, Zhiwei Li, Lili Cao, Shengde Liu… in Genome Biology (2023)

Article

Optimization of glutathione production in Saccharomyces cerevisiae HBSD-W08 using Plackett–Burman and central composite rotatable designs

Glutathione is an important bioactive tripeptide and is widely used in the food, medicine, and cosmetics industries. The aim of this study was to provide an efficient method for producing GSH and to explore it...

**nyi Hu, **nlei Shen, Shen Zhu, Huawei Zeng, Yuying Shuai in BMC Microbiology (2023)

Article

Small protein Cgl2215 enhances phenolic tolerance by promoting MytA activity in Corynebacterium glutamicum

Corynebacterium glutamicum is a promising chassis microorganism for the bioconversion of lignocellulosic biomass owing to its good tolerance and degradation of the inhibitors generated in lignocellulosic pretrea...

Huawei Gu, **nwei Hao, Ruirui Liu, Zhenkun Shi, Zehua Zhao, Fu Chen… in Stress Biology (2022)

Article

Inhibition of KDM5A attenuates cisplatin-induced hearing loss via regulation of the MAPK/AKT pathway

The study aimed to investigate the potential role of lysine-specific demethylase 5A (KDM5A) in cisplatin-induced ototoxicity. The effect of the KDM5A inhibitor CPI-455 was assessed by apoptosis assay, immunofl...

Chang Liu, Zhiwei Zheng, Wen Li, Dongmei Tang… in Cellular and Molecular Life Sciences (2022)