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  1. Article

    Open Access

    MFGE8 in exosomes derived from mesenchymal stem cells prevents esophageal stricture after endoscopic submucosal dissection in pigs

    Endoscopic submucosal dissection (ESD) is the current standard treatment for early-stage esophageal neoplasms. However, the postoperative esophageal stricture after extensive mucosal dissection remains a sever...

    Huasheng Lai, Hon-Chi Yip, Yu Gong, Kai-Fung Chan in Journal of Nanobiotechnology (2024)

  2. Article

    Open Access

    Nanoparticle-assembled bioadhesive coacervate coating with prolonged gastrointestinal retention for inflammatory bowel disease therapy

    A key challenge for the effective treatment of gastrointestinal diseases including inflammatory bowel disease is to develop an orally administered drug delivery system capable of prolonged retention in the gas...

    Pengchao Zhao, **anfeng **a, **ayi Xu, Kevin Kai Chung Leung in Nature Communications (2021)

  3. No Access

    Article

    Bimetallic AgNPs@dopamine modified-halloysite nanotubes-AuNPs for adenine determination using surface-enhanced Raman scattering

    A bimetallic nanoparticles modified halloysite nanotubes (HNTs) hybrid was prepared by embedding AgNPs and modifying AuNPs on the inner or outer wall of dopamine-modified HNTs (DHNTs) in sequence. The resultin...

    Huasheng Lai, Huadong Zhang, Gongke Li, Yufei Hu in Microchimica Acta (2021)

  4. Article

    Open Access

    LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cells

    Chemotherapy resistance is one of the main causes of recurrence in colorectal cancer (CRC) patients and leads to poor prognosis. Long noncoding RNAs (lncRNAs) have been reported to regulate chemoresistance. We...

    **nke Wang, Zhixian Lan, Juan He, Qiuhua Lai, **ang Yao in Cancer Cell International (2019)

  5. No Access

    Article

    Uniform arrangement of gold nanoparticles on magnetic core particles with a metal-organic framework shell as a substrate for sensitive and reproducible SERS based assays: Application to the quantitation of Malachite Green and thiram

    Magnetite (Fe3O4) spheres acting as a core were evenly decorated with gold nanoparticles (AuNPs) and coated with a shell of a metal organic framework (MOF) of type MIL-100(Fe). The resulting hybrid nanomaterial o...

    Huasheng Lai, Wenjuan Shang, Yuyin Yun, Danjiao Chen, Liqian Wu in Microchimica Acta (2019)

  6. No Access

    Article

    A review of the preparation and application of magnetic nanoparticles for surface-enhanced Raman scattering

    In recent years, the unique properties of magnetic functional nanomaterials have received considerable attentions and show promising applications in separation, detection, diagnosis, catalysis, environment rem...

    Huasheng Lai, Fugang Xu, Li Wang in Journal of Materials Science (2018)