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  1. Article

    Open Access

    PITPNC1 Suppress CD8+ T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155

    Radioresistance is a primary factor contributing to the failure of rectal cancer treatment. Immune suppression plays a significant role in the development of radioresistance. We have investigated the potential...

    Junxian Liang, Limin Liao, Lang **e, WenWen Tang in Journal of Translational Medicine (2024)

  2. Article

    Open Access

    Transcription factor expression as a predictor of colon cancer prognosis: a machine learning practice

    Colon cancer is one of the leading causes of cancer deaths in the USA and around the world. Molecular level characters, such as gene expression levels and mutations, may provide profound information for precis...

    Jiannan Liu, Chuanpeng Dong, Guanglong Jiang, **aoyu Lu in BMC Medical Genomics (2020)

  3. Article

    Open Access

    Highly robust model of transcription regulator activity predicts breast cancer overall survival

    While several multigene signatures are available for predicting breast cancer prognosis, particularly in early stage disease, effective molecular indicators are needed, especially for triple-negative carcinoma...

    Chuanpeng Dong, Jiannan Liu, Steven X. Chen, Tianhan Dong in BMC Medical Genomics (2020)

  4. Article

    Open Access

    Dual-gated volumetric modulated arc therapy

    Gated Volumetric Modulated Arc Therapy (VMAT) is an emerging radiation therapy modality for treatment of tumors affected by respiratory motion. However, gating significantly prolongs the treatment time, as del...

    Benjamin Fahimian, Junqing Wu, Huanmei Wu, Sarah Geneser, Lei **ng in Radiation Oncology (2014)