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Book
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Chapter
The Role of Tumor Exosomes in Tumorigenicity
Tumor growth and metastasis is dependent on a complex interplay between the tumor cells and the tumor stroma as well as tumor-tumor interaction. This communication occurs through direct interaction, secreted f...
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Chapter
The Effects of Exosomes and Related Vesicles on Cancer Development, Progression, and Dissemination
Exosomes are small bilayer-membrane-bound nanoparticles that are released from normal, diseased, and neoplastic cells and are present in blood and other bodily fluids. Exosomes contain a variety of signal mole...
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Article
Regulation of apoptosis proteins in cancer cells by ubiquitin
Ubiquitin inhibitors act at many levels to enhance apoptosis signaling. For TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis signaling, there are at least five mechanisms by which apoptosis are...
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Article
Characterization of a SV40-transformed rheumatoid synovial fibroblast cell line which retains genotypic expression patterns: A model for evaluation of anti-arthritic agents
A chimeric Adenovirus-Simian Virus 40 (AdSV40) containing the large T antigen was used to transform rheumatoid synovial fibroblasts. A rheumatoid synovial fibroblast cell line was established by infection of p...