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    Chapter

    The Role of Tumor Exosomes in Tumorigenicity

    Tumor growth and metastasis is dependent on a complex interplay between the tumor cells and the tumor stroma as well as tumor-tumor interaction. This communication occurs through direct interaction, secreted f...

    Huang-Ge Zhang, Johan K. O. Skog in Emerging Concepts of Tumor Exosome–Mediate… (2013)

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    Chapter

    The Effects of Exosomes and Related Vesicles on Cancer Development, Progression, and Dissemination

    Exosomes are small bilayer-membrane-bound nanoparticles that are released from normal, diseased, and neoplastic cells and are present in blood and other bodily fluids. Exosomes contain a variety of signal mole...

    William E. Grizzle M.D. Ph.D. in Emerging Concepts of Tumor Exosome–Mediate… (2013)

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    Article

    Regulation of apoptosis proteins in cancer cells by ubiquitin

    Ubiquitin inhibitors act at many levels to enhance apoptosis signaling. For TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis signaling, there are at least five mechanisms by which apoptosis are...

    Huang-Ge Zhang, Jianhua Wang, **nwen Yang, Hui-Chen Hsu, John D Mountz in Oncogene (2004)

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    Article

    Characterization of a SV40-transformed rheumatoid synovial fibroblast cell line which retains genotypic expression patterns: A model for evaluation of anti-arthritic agents

    A chimeric Adenovirus-Simian Virus 40 (AdSV40) containing the large T antigen was used to transform rheumatoid synovial fibroblasts. A rheumatoid synovial fibroblast cell line was established by infection of p...

    Huang-Ge Zhang, Warren D. Blackburn Jr. in In Vitro Cellular & Developmental Biology … (1997)