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Article
Nicotine Inhibits Microglial Proliferation and Is Neuroprotective in Global Ischemia Rats
Ischemic injury in rodent models reliably leads to the activation of microglia, which might play a detrimental role in neuronal survival. Our preliminary studies suggest that nicotine plays a potential role in...
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Article
Astrocyte-derived ATP modulates depressive-like behaviors
Astrocytic dysfunction is a common feature in the brains of depressed subjects. Now, **n-Hong Zhu and colleagues show that astrocytic release of ATP is reduced in the brains of stressed mice and that restoring...
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Article
An L-Type Calcium Channel Agonist, Bay K8644, Extends the Window of Intervention Against Ischemic Neuronal Injury
Our previous data indicate that the inhibition of L-type calcium channels (LTCCs) might be the cause of post-ischemic neuronal injury and that the activation of LTCCs can give rise to neuroprotection. In the p...