108 Result(s)
within
Hua** Zhu
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessA(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases
Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was introduced from avian sources during the 1957 pan...
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Open AccessImpact analysis of digital trade on carbon emissions from the perspectives of supply and demand
Amidst the escalating challenge of global climate change, it is imperative to further explore whether digital trade, as an emerging element in the global development landscape, can reduce carbon emissions and ...
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Open AccessThe changes in ocular torsion after unilateral lateral rectus recession-medial rectus resection for intermittent exotropia
We aim to explore the alterations of objective ocular torsion after unilateral lateral rectus recession-medial rectus resection (R&R) for intermittent exotropia (IXT). Seventy-two IXT patients undergoing R&R b...
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Open AccessIdentification and characterization of Varicella Zoster Virus circular RNA in lytic infection
This study investigates the role of circular RNAs (circRNAs) in the context of Varicella-Zoster Virus (VZV) lytic infection. We employ two sequencing technologies, short-read sequencing and long-read sequencin...
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Single-cell transcriptome analysis reveals the regulatory functions of islet exocrine cells after short-time obesogenic diet
This study aims to investigate the functions of exocrine islet cell subtypes in the early stage of obesity induced by high-fat diet (HFD), which is accompanied with deterioration of the systemic insulin respon...
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Open AccessUncovering the essence of diverse media biases from the semantic embedding space
Media bias widely exists in the articles published by news media, influencing their readers’ perceptions, and bringing prejudice or injustice to society. However, current analysis methods usually rely on human...
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Open AccessUniversal inter-molecular radical transfer reactions on metal surfaces
On-surface synthesis provides tools to prepare low-dimensional supramolecular structures. Traditionally, reactive radicals are a class of single-electron species, serving as exceptional electron-withdrawing gr...
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Open AccessBacPE: a versatile prime-editing platform in bacteria by inhibiting DNA exonucleases
Prime editing allows precise installation of any single base substitution and small insertions and deletions without requiring homologous recombination or double-strand DNA breaks in eukaryotic cells. However,...
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Open AccessACS-20/FATP4 mediates the anti-ageing effect of dietary restriction in C. elegans
Dietary restriction is an effective anti-ageing intervention across species. However, the molecular mechanisms from the metabolic aspects of view are still underexplored. Here we show ACS-20 as a key mediator ...
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Open AccessIntranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants and “anatomical escape” characteristics threaten the effectiveness of current coronavirus disease 2019 (COVID-19) vaccines...
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Open AccessPregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions
Citrus fruit has long been considered a healthy food, but its role and detailed mechanism in lifespan extension are not clear. Here, by using the nematode C. elegans, we identified that nomilin, a bitter-taste li...
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Open AccessSelective conversion of CO2 to isobutane-enriched C4 alkanes over InZrOx-Beta composite catalyst
Direct conversion of CO2 to a single specific hydrocarbon with high selectivity is extremely attractive but very challenging. Herein, by employing an InZrOx-Beta composite catalyst in the CO2 hydrogenation, a hig...
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Open AccessPCSK9, a novel immune and ferroptosis related gene in abdominal aortic aneurysm neck
The gene expression profile of abdominal aortic aneurysm (AAA) neck is not fully understood. The etiology of AAA is considered to be related to atherosclerosis and the inflammatory response, involving congenit...
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The clinical characteristics of patients with normotension in pheochromocytomas and paragangliomas
The predominant symptom of pheochromocytomas and paragangliomas (PPGLs) is variable hypertension (HTN); however, not all patients with PPGLs develop HTN. Studies of the clinical characteristics of normotensive...
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Open AccessTRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models
Although radiotherapy can promote antitumour immunity, the mechanisms underlying this phenomenon remain unclear. Here, we demonstrate that the expression of the E3 ubiquitin ligase, tumour cell-intrinsic tripa...
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Open AccessA miniaturized bionic ocean-battery mimicking the structure of marine microbial ecosystems
Marine microbial ecosystems can be viewed as a huge ocean-battery charged by solar energy. It provides a model for fabricating bio-solar cell, a bioelectrochemical system that converts light into electricity. ...
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Open AccessTranscriptome analysis provides insights into the molecular mechanism of GhSAMDC1 involving in rapid vegetative growth and early flowering in tobacco
In previous study, ectopic expression of GhSAMDC1 improved vegetative growth and early flowering in tobacco, which had been explained through changes of polyamine content, polyamines and flowering relate genes ex...
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Open AccessCHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity
Natural killer (NK) cells are known to mediate killing of various cancer types, but tumor cells can develop resistance mechanisms to escape NK cell-mediated killing. Here, we use a “two cell type” whole genome...
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Open AccessSelective photocatalytic CO2 reduction in aerobic environment by microporous Pd-porphyrin-based polymers coated hollow TiO2
Direct photocatalytic CO2 reduction from primary sources, such as flue gas and air, into fuels, is highly desired, but the thermodynamically favored O2 reduction almost completely impedes this process. Herein, we...
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Open AccessDevelopment of a skin- and neuro-attenuated live vaccine for varicella
Varicella caused by the primary infection of varicella-zoster virus (VZV) exerts a considerable disease burden globally. Current varicella vaccines consisting of the live-attenuated vOka strain of VZV are gene...
