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  1. Article

    Open Access

    DNMT3b protects centromere integrity by restricting R-loop-mediated DNA damage

    This study used DNA methyltransferase 3b (DNMT3b) knockout cells and the functional loss of DNMT3b mutation in immunodeficiency-centromeric instability-facial anomalies syndrome (ICF) cells to understand how D...

    Hsueh-Tzu Shih, Wei-Yi Chen, Hsin-Yen Wang, Tung Chao in Cell Death & Disease (2022)

  2. Article

    Open Access

    Integrating RNA-seq and ChIP-seq data to characterize long non-coding RNAs in Drosophila melanogaster

    Recent advances in sequencing technology have opened a new era in RNA studies. Novel types of RNAs such as long non-coding RNAs (lncRNAs) have been discovered by transcriptomic sequencing and some lncRNAs have...

    Mei-Ju May Chen, Li-Kai Chen, Yu-Shing Lai, Yu-Yu Lin, Dung-Chi Wu in BMC Genomics (2016)