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Article

A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis

CTLA4Ig is a dimeric fusion protein of the extracellular domain of cytotoxic T-lymphocyte protein 4 (CTLA4) and an Fc (Ig) fragment of human IgG₁ that is approved for treating rheumatoid arthritis. However, CTLA4...

Fu-Yao Jiang, Yan-Zhu Zhang, Yuan-Hong Tai, Chien-Yu Chou… in Inflammation and Regeneration (2023)