Skip to main content

and
  1. Article

    Open Access

    Synergizing MBR and MCDI systems as a sustainable solution for decentralized wastewater reclamation and reuse

    Decentralized wastewater reclamation and reuse systems have drawn much attention due to their capability for reducing the energy demand for water conveyance and reclaiming wastewater for local re-use. While me...

    Wang-Sheng Yu, Huei-Cih Liu, Hsin-Chieh Lin in Sustainable Environment Research (2024)

  2. Article

    Open Access

    Stem cell exosome-loaded Gelfoam improves locomotor dysfunction and neuropathic pain in a rat model of spinal cord injury

    Spinal cord injury (SCI) is a debilitating illness in humans that causes permanent loss of movement or sensation. To treat SCI, exosomes, with their unique benefits, can circumvent limitations through direct s...

    Raju Poongodi, Tao-Hsiang Yang, Ya-Hsien Huang in Stem Cell Research & Therapy (2024)

  3. Article

    Open Access

    A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis

    CTLA4Ig is a dimeric fusion protein of the extracellular domain of cytotoxic T-lymphocyte protein 4 (CTLA4) and an Fc (Ig) fragment of human IgG1 that is approved for treating rheumatoid arthritis. However, CTLA4...

    Fu-Yao Jiang, Yan-Zhu Zhang, Yuan-Hong Tai, Chien-Yu Chou in Inflammation and Regeneration (2023)

  4. Article

    Open Access

    Identification of Methylation-Driven, Differentially Expressed STXBP6 as a Novel Biomarker in Lung Adenocarcinoma

    DNA methylation is an essential epigenetic marker associated with the silencing of gene expression. Although various genome-wide studies revealed aberrantly methylated gene targets as molecular biomarkers for ...

    Govinda Lenka, Mong-Hsun Tsai, Hsin-Chieh Lin, Jen-Hao Hsiao in Scientific Reports (2017)

  5. Article

    Open Access

    Rapid decrease in tumor perfusion following VEGF blockade predicts long-term tumor growth inhibition in preclinical tumor models

    Vascular endothelial growth factor (VEGF) is a key upstream mediator of tumor angiogenesis, and blockade of VEGF can inhibit tumor angiogenesis and decrease tumor growth. However, not all tumors respond well t...

    Alexandra Eichten, Alexander P. Adler, Blerta Cooper, Jennifer Griffith in Angiogenesis (2013)

  6. Article

    Open Access

    Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling

    The wounding response relies on tightly regulated crosstalk between recruited fibroblasts and the collagenous extracellular matrix (ECM). Discoidin domain receptor 2 (DDR2) is a tyrosine kinase receptor for fi...

    Elvira Olaso, Hsin-Chieh Lin, Li-Hsien Wang in Fibrogenesis & Tissue Repair (2011)

  7. No Access

    Chapter and Conference Paper

    AIMED- A Personalized TV Recommendation System

    Previous personalized DTV recommendation systems focus only on viewers’ historical viewing records or demographic data. This study proposes a new recommending mechanism from a user oriented perspective. The re...

    Shang H. Hsu, Ming-Hui Wen, Hsin-Chieh Lin in Interactive TV: a Shared Experience (2007)

  8. No Access

    Article

    Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

    Tumour growth requires accompanying expansion of the host vasculature, with tumour progression often correlated with vascular density. Vascular endothelial growth factor (VEGF) is the best-characterized induce...

    Irene Noguera-Troise, Christopher Daly, Nicholas J. Papadopoulos, Sandra Coetzee in Nature (2006)