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Article
Aprepitant, fosaprepitant and risk of ifosfamide-induced neurotoxicity: a systematic review
Ifosfamide is one of the chemotherapy regimens which potentially causes neurotoxicity in patients up to 30%. Aprepitant is administered as an anti-emetic agent in chemotherapy and regarding the inhibitory effe...
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Chapter
Radiosensitizers in Radiation-Induced Cancer Therapy
Radiation therapy (RT) has established as a very auspicious tool to tackle cancer, but its efficacy has encountered with some challenges. As we all know, in the case of cancer therapy by RT, high doses of radi...
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Article
Open AccessHTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions
Adult T-cell leukemia/lymphoma (ATLL) is a lymphoproliferative disorder of HTLV-1-host interactions in infected TCD4+ cells. In this study, the HTLV-1 proviral load (PVL) and HBZ as viral elements and AKT1, BAD,
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Article
Open AccessThe combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” micro-environment in patients with adult T-cell leukemia lymphoma
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Article
Open AccessThe combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” cytokine expression profile in patients with adult T-cell leukemia lymphoma
HTLV-I associated adult T-cell leukemia/lymphoma (ATL) carries a dismal prognosis due to chemo-resistance and immuno-compromised micro-environment. The combination of zidovudine and interferon-alpha (IFN) sign...