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Article
Open AccessGenotypes of cancer stem cells characterized by epithelial-to-mesenchymal transition and proliferation related functions
Cancer stem cells (CSCs), or cancer cells with stem cell-like properties, generally exhibit drug resistance and have highly potent cancer inducing capabilities. Genome-wide expression data collected at public ...
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Article
Universality in large-scale structure of complete genomes
The abundance of duplications in genomes in the form of paralogs, pseudogenes and a variety of repeats suggests that genomes may have used duplications as one mode for their growth. However a systematic knowle...
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Article
Short segmental duplication: parsimony in growth of microbial genomes
We compare the distributions of occurrence frequencies of oligonucleotides two to ten bases long (2 to 10-mers) in microbial complete genomes with corresponding distributions obtained from random sequences and...