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  1. Article

    Open Access

    Genotypes of cancer stem cells characterized by epithelial-to-mesenchymal transition and proliferation related functions

    Cancer stem cells (CSCs), or cancer cells with stem cell-like properties, generally exhibit drug resistance and have highly potent cancer inducing capabilities. Genome-wide expression data collected at public ...

    Chueh-Lin Hsu, Feng-Hsiang Chung, Chih-Hao Chen, Tzu-Ting Hsu in Scientific Reports (2016)

  2. Article

    Universality in large-scale structure of complete genomes

    The abundance of duplications in genomes in the form of paralogs, pseudogenes and a variety of repeats suggests that genomes may have used duplications as one mode for their growth. However a systematic knowle...

    Li-Ching Hsieh, Ta-Yuan Chen, Chang-Heng Chang, Wen-Lang Fan in Genome Biology (2004)

  3. Article

    Short segmental duplication: parsimony in growth of microbial genomes

    We compare the distributions of occurrence frequencies of oligonucleotides two to ten bases long (2 to 10-mers) in microbial complete genomes with corresponding distributions obtained from random sequences and...

    Li-Ching Hsieh, Liaofu Luo, Hoong-Chien Lee in Genome Biology (2003)