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Chapter and Conference Paper
A Parallel Slime Mould Algorithm with Boundary Rebound and Knowledge-Sharing Mechanism
The conventional slime mould method has high global search ability but has certain drawbacks such as sluggish convergence speed, limited accuracy, and the tendency to slip into a locally optimum solution. Aimi...
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Article
TLR7, a third signal for the robust generation of spontaneous germinal center B cells in systemic lupus erythematosus
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Article
Activation of TLR7 increases CCND3 expression via the downregulation of miR-15b in B cells of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by B-cell hyperreactivity. The Toll-like receptor 7 (TLR7) signaling pathway is abnormally activated in SLE B cells. CyclinD3 (CCND3) p...
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Article
Open AccessNotch-Hes-1 axis controls TLR7-mediated autophagic death of macrophage via induction of P62 in mice with lupus
The increased death of macrophages has been considered as a pathogenic factor for systemic lupus erythematosus (SLE), and dysfunction of autophagy may contribute to improper cell death. However, the effect of ...
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Article
Open AccessDifferential expression of microRNAs in decidua-derived mesenchymal stem cells from patients with pre-eclampsia
Mesenchymal stem cells (MSCs) at maternal-fetal interface are considered to play an important role in the pathogenesis of pre-eclampsia (PE). microRNAs (miRNAs) also have an important influence on differentiat...
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Article
Pre-treatment with IL-1β enhances the efficacy of MSC transplantation in DSS-induced colitis
Mesenchymal stem cells (MSCs) have been used experimentally for treating inflammatory disorders, partly due to their immunosuppressive properties. Although interleukin-1β (IL-1β) is one of the most important i...
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Article
Lymphocyte subpopulations in Chinese women with Turner syndrome
Turner syndrome (TS) is associated with deficiency of cellular and humoral immunity. However, the characteristics of lymphocyte subpopulations in Chinese women with TS have not been reported. In this study, th...