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  1. Article

    Open Access

    Development and validation of a nomogram to predict long-term cancer-specific survival for patients with osteosarcoma

    The present work aimed to establish a new model to accurately estimate overall survival (OS) as well as cancer-specific survival (CSS) of osteosarcoma. Osteosarcoma cases were collected from the Surveillance, ...

    Yali Yu, Shaohua Wang, Jia Liu, Jiejie Ge, Hongya Guan in Scientific Reports (2023)

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  2. Article

    Open Access

    miR-27a attenuates adipogenesis and promotes osteogenesis in steroid-induced rat BMSCs by targeting PPARγ and GREM1

    The imbalance between adipogenic and osteogenic differentiation in bone marrow mesenchymal stem cells (BMSCs) plays a significant role in the pathogenesis of steroid-induced osteonecrosis of the femoral head (...

    Chenxi Gu, Yan Xu, Shanfeng Zhang, Hongya Guan, Shi Song, **uli Wang… in Scientific Reports (2016)

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  3. No Access

    Article

    Upregulation of miR-192 inhibits cell growth and invasion and induces cell apoptosis by targeting TCF7 in human osteosarcoma

    MicroRNAs (miRNAs) can function as oncogenes or tumor suppressor genes and are involved in multiple processes in cancer development and progression. For example, miR-192 is dysregulated in multiple human cance...

    Yadong Wang, Shanfeng Zhang, Yan Xu, Yan Zhang, Hongya Guan, **njie Li… in Tumor Biology (2016)