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  1. Article

    Open Access

    sST2: A Bridge Between Sirt1/p53/p21 Signal-Induced Senescence and TGF-β1/Smad2/3 Regulation of Cardiac Fibrosis in Mouse Viral Myocarditis

    Soluble interleukin 1 receptor-like 1 (sST2) is a novel predictor of poor outcomes, which is involved in inflammatory response and fibrosis of myocarditis. Cellular senescence is a state of irreversible cell c...

    Jiajia Tan, **g Wei, Hongxiang Lu in Inflammation (2023)

  2. Article

    Open Access

    Retraction Note: HMGB1 Facilitated Macrophage Reprogramming towards a Proinflammatory M1-like Phenotype in Experimental Autoimmune Myocarditis Development

    Zhaoliang Su, Pan Zhang, Ying Yu, Hongxiang Lu, Yanfang Liu, ** Ni in Scientific Reports (2022)

  3. Article

    Open Access

    Plasma Vanin-1 as a Novel Biomarker of Sepsis for Trauma Patients: A Prospective Multicenter Cohort Study

    Vanin-1 plays a pivotal role in oxidative stress and the inflammatory response. However, its relationship with traumatic sepsis remains unknown. The aim of our study was to evaluate whether plasma vanin-1 coul...

    Hongxiang Lu, Anqiang Zhang, Dalin Wen, Juan Du in Infectious Diseases and Therapy (2021)

  4. Article

    Open Access

    Emergency trauma care during the outbreak of corona virus disease 2019 (COVID-19) in China

    A novel coronavirus pneumonia outbreak began in Wuhan, Hubei Province, in December 2019; the outbreak was caused by a novel coronavirus previously never observed in humans. China has imposed the strictest quar...

    Yang Li, Ling Zeng, Zhanfei Li, Qingxiang Mao in World Journal of Emergency Surgery (2020)

  5. No Access

    Article

    MiR-608 Exerts Anti-inflammatory Effects by Targeting ELANE in Monocytes

    miR-608 has been indicated to play an important role in the pathogenesis of various inflammation-related diseases, including sepsis and several types of cancers. However, there is little information about the ...

    Wei Gu, Dalin Wen, Hongxiang Lu, Anqiang Zhang in Journal of Clinical Immunology (2020)

  6. Article

    Open Access

    Enhancer polymorphism rs10865710 associated with traumatic sepsis is a regulator of PPARG gene expression

    Peroxisome proliferator-activated receptor gamma (PPARγ) is a major regulator in sepsis. Our previous study identified the enhancer polymorphism rs10865710C/G to be associated with susceptibility to sepsis in ...

    Hongxiang Lu, Dalin Wen, Jianhui Sun, Ling Zeng, Juan Du, Dingyuan Du in Critical Care (2019)

  7. Article

    Open Access

    Host genetic variants in sepsis risk: a field synopsis and meta-analysis

    Published data revealed that host genetic variants have a substantial influence on sepsis susceptibility. However, the results have been inconsistent. We aimed to systematically review the published studies an...

    Hongxiang Lu, Dalin Wen, Xu Wang, Lebin Gan, Juan Du, Jianhui Sun in Critical Care (2019)

  8. Article

    Open Access

    Transcriptome and key genes expression related to carbon fixation pathways in Chlorella PY-ZU1 cells and their growth under high concentrations of CO2

    The biomass yield of Chlorella PY-ZU1 drastically increased when cultivated under high CO2 condition compared with that cultivated under air condition. However, less attention has been given to the microalgae pho...

    Yun Huang, Jun Cheng, Hongxiang Lu, Yong He, Junhu Zhou in Biotechnology for Biofuels (2017)

  9. Article

    Open Access

    RETRACTED ARTICLE: HMGB1 Facilitated Macrophage Reprogramming towards a Proinflammatory M1-like Phenotype in Experimental Autoimmune Myocarditis Development

    Macrophages can be reprogramming, such as the classical activated macrophage, M1 or alternative activated macrophages, M2 phenotype following the milieu danger signals, especially inflammatory factors. Macroph...

    Zhaoliang Su, Pan Zhang, Ying Yu, Hongxiang Lu, Yanfang Liu, ** Ni in Scientific Reports (2016)