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Article
Metabolomics signature of blood pressure salt sensitivity and its link to cardiovascular disease: A dietary salt-intervention trial
Individuals with a high degree of salt sensitivity (SS) have a greater risk of cardiovascular disease (CVD), but whether SS fosters CVD by influencing metabolomics homeostasis remains unclear. This study aimed...
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Chapter and Conference Paper
Anti-glare Angle Design and Simulation of Automotive Central Control Screen
The anti-glare angle design and simulation is critical in the automotive central control screen, however it has an issue with erroneous performance positioning. The typical Rendering techniques is unable to ad...
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Article
Industrial IoT–enabled real-time prediction of strip cross-section shape for hot-rolling steel
Because strip cross sections cannot be obtained during hot rolling in advance, traditional automatic shape control systems can only rely on the measured shape at the exit of the final mill for feedback control...
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Article
Associations of NADPH oxidase-related genes with blood pressure changes and incident hypertension: The GenSalt Study
Previous studies have indicated that reactive oxygen species produced by NADPH oxidase (Nox) are important risk factors of hypertension. The current study aims to examine the associations of Nox-related genes ...
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Article
Association study of common variations of FBN1 gene and essential hypertension in Han Chinese population
Fibrillin-1 (FBN1) was reported to have impact on the physiological arterial stiffness and vascular remodeling with hypertension of recent years. In the previous study we reported the association of four funct...
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Article
Genome-wide association study in Han Chinese identifies three novel loci for human height
Human height is a complex genetic trait with high heritability but discovery efforts in Asian populations are limited. We carried out a meta-analysis of genome-wide association studies (GWAS) for height in 6,5...
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Article
Association of adrenomedullin gene polymorphisms and blood pressure in a Chinese population
Genetic factors may determine an individual’s blood pressure (BP) level and risk for hypertension. This study aimed to examine the associations between genetic variants of the adrenomedullin (ADM) gene and essent...
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Article
Association between genetic variants of the ADD1 and GNB3 genes and blood pressure response to the cold pressor test in a Chinese Han population: the GenSalt Study
Genetic factors influence blood pressure (BP) response to the cold pressor test (CPT), which is a phenotype related to hypertension risk. We examined the association between variants of the α-adducin (ADD1) and g...
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Article
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease
Dongfeng Gu and colleagues report a genome-wide association study for coronary artery disease in Han Chinese individuals. They identify four loci newly associated with coronary artery disease.
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Article
Open AccessFunctional analysis of the C-reactive protein (CRP) gene -717A>G polymorphism associated with coronary heart disease
Atherosclerosis underlies the major pathophysiological mechanisms of coronary heart disease (CHD), and inflammation contributes to all phases of atherosclerosis. C-reactive protein (CRP), a sensitive, but nons...
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Article
Renalase gene is a novel susceptibility gene for essential hypertension: a two-stage association study in northern Han Chinese population
Renalase, a novel flavin adenine dinucleotide-dependent amine oxidase, is secreted by the kidney, degrades circulating catecholamines, and modulates cardiac function and systemic blood pressure (BP). Its disco...
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Article
Common variation in KLKB1 and essential hypertension risk: tagging-SNP haplotype analysis in a case-control study
The human plasma kallikrein gene (KLKB1) encodes plasma kallikrein, a serine protease that catalyzes the release of kinins and other vasoactive peptides and may be involved in the pathogenesis of hypertension....
