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Article
Open AccessHeat stress affects mammary metabolism by influencing the plasma flow to the glands
Environmental heat stress (HS) can have detrimental effects on milk production by compromising the mammary function. Mammary plasma flow (MPF) plays a crucial role in nutrient supply and uptake in the mammary ...
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Article
Open AccessChanges of brain functional network in Alzheimer’s disease and frontotemporal dementia: a graph-theoretic analysis
Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are the two most common neurodegenerative dementias, presenting with similar clinical features that challenge accurate diagnosis. Despite extensive re...
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Article
Open AccessOptimized BEAC conditioning regimen improves clinical outcomes of autologous hematopoietic stem cell transplantation in non-Hodgkin lymphomas
The conditioning regimen is an important part of autologous hematopoietic stem cell transplantation (ASCT). We explored the efficacy and safety of an optimized BEAC (adjusted-dose, intermediate-dose cytarabine...
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Article
Open AccessCre recombinase promotes leukemogenesis in the presence of both homozygous and heterozygous FLT3-ITD
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Article
From cross-lagged effects to feedback effects: Further insights into the estimation and interpretation of bidirectional relations
Bidirectional relations have long been of interest in psychology and other social behavioral sciences. In recent years, the widespread use of intensive longitudinal data has provided new opportunities to exami...
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Article
Polytomous Effectiveness Indicators in Complex Problem-Solving Tasks and Their Applications in Develo** Measurement Model
Recent years have witnessed the emergence of measurement models for analyzing action sequences in computer-based problem-solving interactive tasks. The cutting-edge psychometrics process models require pre-spe...
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Article
A Mixture Modeling Approach to Detect Different Behavioral Patterns for Process Data
Process data recorded by computer-based assessments reflect how respondents solve problems and thus contain rich information about respondents as well as tasks. Considering that different respondents may exhib...
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Article
Open AccessUtilizing molecular docking and cell validation to explore the potential mechanisms of lupenone attenuating the inflammatory response via NF‐κB pathway
Diabetic nephropathy (DN), a common microvascular complicating disease of diabetes. Lupenone, a pentacyclic triterpenoid, has anti-inflammatory effects and can prevent type 2 diabetes mellitus and treat renal ...
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Article
A state response measurement model for problem-solving process data
In computer simulation-based interactive tasks, different people make different response processes to the same tasks, resulting in various action sequences. These sequences contain rich information, not only a...
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Article
Estimation of individuals’ collaborative problem solving ability in computer-based assessment
In the human-to-human Collaborative Problem Solving (CPS) test, students’ problem-solving process reflects the interdependency among partners. The high interdependency in CPS makes it very sensitive to group c...
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Article
Open AccessCorilagin enhances the anti-tumor activity of 5-FU by downregulating the expression of GRP 78
Colorectal cancer is one of the most common malignancies worldwide. Although initially effective, patients who receive chemotherapy ultimately experience various complications and develop chemo-resistance, lea...
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Article
Victim profiles and the protective role of school anti-bullying norms: a study of Chinese adolescents
Profiling victimization and examining the role of school protective factors could help educators to intervene in bullying effectively. To advance a more comprehensive understanding of bullying victimization, b...
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Article
Open AccessDifferences in intestinal motility during different sleep stages based on long-term bowel sounds
This study focused on changes in intestinal motility during different sleep stages based on long-term bowel sounds.
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Article
Open AccessHeat stress affects dairy cow health status through blood oxygen availability
Rises in global warming and extreme weather occurrence make the risk of heat stress (HS) induced by high ambient temperatures more likely in high-yielding dairy cows, resulting in low milk quality and yield. I...
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Article
Open AccessApplication of platelet-rich plasma (PRP) in lips rejuvenation
In recent years, minimally invasive and non-invasive rejuvenation methods have been welcomed. PRP has been used widely for skin rejuvenation, but there are few studies on PRP for lip rejuvenation.
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Article
Open AccessRobust-PAC time-critical workflow offloading in edge-to-cloud continuum among heterogeneous resources
Edge-to-cloud continuum connects and extends the calculation from edge side via network to cloud platforms, where diverse workflows go back and forth, getting executed on scheduled calculation resources. To be...
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Article
Teacher-student relationship as a protective factor for socioeconomic status, students’ self-efficacy and achievement: a multilevel moderated mediation analysis
This study examined whether the teacher-student relationship (TSR) served as a protective factor for students from families of lower socioeconomic status (SES). It was based on data from a standard mathematics...
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Article
Open AccessRobust and accurate performance anomaly detection and prediction for cloud applications: a novel ensemble learning-based framework
Effectively detecting run-time performance anomalies is crucial for clouds to identify abnormal performance behavior and forestall future incidents. To be used for real-world applications, an effective anomaly...
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Article
Automated and interactive game-based assessment of critical thinking
Critical thinking is one of the important higher-order skills very much treasured in education, but hard to be measured using paper-pencil tests. In line with recent recommendation to measure high-order thinki...
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Article
Two-level moderated mediation models with single-level data and new measures of effect sizes
This article proposes a two-level moderated mediation (2moME) model with single level data, and develops measures to quantify the moderated mediation (moME) effect sizes for both the conventional moME model an...
