5 Result(s)
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HongLian Li
Biomedicine
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Article
Open AccessHeparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer’s disease
Defective amyloid-β (Aβ) clearance from the brain is a major contributing factor to the pathophysiology of Alzheimer’s disease (AD). Aβ clearance is mediated by macrophages, enzymatic degradation, perivascular...
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Article
Open AccessIdentification of cucurbit chlorotic yellows virus P4.9 as a possible movement protein
Cucurbit chlorotic yellows virus (CCYV) is a bipartite cucurbit-infecting crinivirus within the family Closteroviridae. The crinivirus genome varies among genera. P4.9 is the first protein encoded by CCYV RNA2. P...
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Article
Open AccessSET SUMOylation promotes its cytoplasmic retention and induces tau pathology and cognitive impairments
PP2A is a major regulator of tau phosphorylation, which is principally regulated by an endogenous nuclear protein inhibitor 2 of PP2A (I2PP2A), also named SET. However, how SET is post-translationally regulated a...
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Article
Open AccessDevelopment of a GFP expression vector for Cucurbit chlorotic yellows virus
Cucurbit chlorotic yellows virus (CCYV), a bipartite crinivirus, causes chlorotic leaf spots and yellowing symptoms on cucurbit leaves. We previously developed an infectious clone of CCYV. Limited work has been c...
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Article
Open AccessTranscriptome analysis of Cucumis sativus infected by Cucurbit chlorotic yellows virus
Cucurbit chlorotic yellows virus (CCYV) is a recently reported bipartite crinivirus that causes chlorotic leaf spots and yellowing symptoms on the leaves of cucurbit plants. The virus–...
