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Article
Open AccessLecithin nano-liposomal particle as a CRISPR/Cas9 complex delivery system for treating type 2 diabetes
Protein-based Cas9 in vivo gene editing therapeutics have practical limitations owing to their instability and low efficacy. To overcome these obstacles and improve stability, we designed a nanocarrier primari...
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Chapter and Conference Paper
Relationship Among Dislocation Density, Local Strain Distribution, and PWSCC Susceptibility of Alloy 690
The effects of local strain distribution on primary water stress corrosion cracking of cold-rolled Alloy 690 with an inhomogeneous microstructure were investigated by measuring dislocation densities using tran...
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Article
The novel resveratrol derivative 3,5-diethoxy-3′,4′-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a well-known polyphenol that is present in grapes, peanuts, pine seeds, and several other plants. Resveratrol exerts deleterious effects on various types of human...
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Article
Investigation of oxide property on Alloy 600 with the immersion time in a high-temperature leaded alkaline solution
Oxide on a stress corrosion cracked region of TT Alloy 600 exposed to a nuclear power plant for over 20 years was analyzed using TEM-EDS for a sample prepared by an FIB. Pb above 10 wt% was observed in the oxi...
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Article
Ex situ and in situ characterization of stress corrosion cracking of nickel-base alloys at high temperature
Recent ex situ and in situ characterization of the major factors influencing primary water stress corrosion cracking (PWSCC) and outside diameter stress corrosion cracking (ODSCC) of nickel-base alloys of Allo...
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Article
Open AccessCarbon monoxide inhibits Fas activating antibody-induced apoptosis in endothelial cells
The extrinsic apoptotic pathway initiates when a death ligand, such as the Fas ligand, interacts with its cell surface receptor (ie., Fas/CD95), forming a death-inducing signaling complex (DISC). The Fas-dependen...
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Article
Evaluation of electrodeposited ternary Ni-alloys for thermal stability
Electroplating methods for ternary Ni-alloys, such as Ni-P-Fe and Ni-P-B, in a Ni sulfamate solution on the inner wall surfaces of Alloy 600 tubing have been developed in order to use them to repair steam gene...
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Article
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Autophagy is a physiological process that involves the engulfment and degradation of organelles. Choi and colleagues demonstrate that autophagy is important for the removal of damaged mitochondria and thus the...
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Article
Stress corrosion cracking of alloy 600 in an aqueous solution containing lead oxide
The stress corrosion cracking (SCC) behavior of Alloy 600 was studied in aqueous solutions containing lead. Electrochemical polarization and current transient experiments were performed at 315 °C in a 40% sodi...
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Article
Electro-deposition of oxide-dispersed nickel composites and the behavior of their mechanical properties
Oxide-dispersed nickel composites were produced by electro-deposition of nickel with various types of oxide nano-powders in a sulfamate bath. The effect of the oxide concentration in the bath on the mechanical...
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Chapter
Apoptosis in Lung Injury and Disease
Pulmonary cell death may contribute significantly to acute and chronic lung injuries caused by various adverse environmental agents. Pulmonary cells may die by necrosis, apoptosis, and other forms of regulated...
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Article
Performance of NiB inhibitor for PbSCC of alloy 600 in Pb-contaminated water and caustic solutions
Nickel-based iron-chromium alloys are used as steam generator (SG) tubing materials in nuclear power plants (NPPs) but experience intergranular stress corrosion cracking (IGSCC) and lead stress corrosion crack...
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Article
Caustic stress corrosion cracking of alloys 600 and 690 with NaOH concentrations
In order to evaluate the stress corrosion cracking resistance for commercial alloys (C600MA, C600TT, C690TT) and Korean-made alloys (K600MA, K690TT), C-ring tests were performed in a caustic environment of 4, ...
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Article
Antihepatotoxic zeaxanthins from the fruits ofLycium chinense
A CHCl3: MeOH extract of the fruit ofLycium chinense Mill. (Solanaceae) was found to afford significant protection against carbon tetrachloride-induced toxicity in primary cultures of rat hepatocytes. Subsequent ...
