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Article
Open AccessDifferential CpG methylation at Nnat in the early establishment of beta cell heterogeneity
Beta cells within the pancreatic islet represent a heterogenous population wherein individual sub-groups of cells make distinct contributions to the overall control of insulin secretion. These include a subpop...
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Article
Open AccessSexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis
Variants close to the VPS13C/C2CD4A/C2CD4B locus are associated with altered risk of type 2 diabetes in genome-wide association studies. While previous functional work has suggested roles for VPS13C and C2CD4A in...