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Article
Open AccessSignificance of definitive concurrent chemoradiotherapy for vulvar cancer: a Japanese Gynecologic Oncology Group nationwide survey study
This study aimed to show the results of radical radiation therapy (RT) and concurrent chemoradiotherapy (CCRT) for vulvar cancer (VC) based on data from a Japanese nationwide survey.
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Article
Unveiling the mille-feuille sign: a key to diagnosing ovarian carcinosarcoma in addition to ovarian metastasis from colorectal carcinoma on MRI
To clarify the diagnostic utility and formation of the Mille-feuille sign for ovarian carcinosarcoma (OCS) on MRI, and to evaluate the other MRI findings and serum markers compared to ovarian metastases from c...
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Article
Prediction of response to promising first-line chemotherapy in ovarian cancer patients with residual peritoneal tumors: practical biomarkers and robust multiplex models
Platinum/taxane (TC) chemotherapy with debulking surgery stays the mainstay of the treatment in ovarian cancer patients with peritoneal metastasis, and recently its novel modality, intraperitoneal carboplatin ...
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Article
Clinical relevance of reversible cerebral vasoconstriction syndrome in pregnant women with posterior reversible encephalopathy syndrome: review of case reports in Japan
We systematically reviewed case reports of posterior reversible encephalopathy syndrome (PRES), and investigated the characteristics of PRES in pregnant Japanese women and the clinical relevance of reversible ...
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Article
Automated electrochemiluminescence immunoassay for serum PlGF levels in women with singleton pregnancy at 9–13 weeks of gestation predicts preterm preeclampsia: a retrospective cohort study
Our aims were to obtain the gestational-age-specific median of common logarithmic placental growth factor (PlGF) values in the first trimester in women with a singleton pregnancy in order to generate the gesta...
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Chapter and Conference Paper
Development of an Estimation Method for the Seismic Motion Reproducibility of a Three-Dimensional Ground Structure Model by Combining Surface-Observed Seismic Motion and Three-Dimensional Seismic Motion Analysis
The ground structure can substantially influence seismic ground motion underscoring the need to develop a ground structure model with sufficient reliability in terms of ground motion estimation for earthquake ...
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Article
H3K27me3 deficiency in dedifferentiated carcinoma and carcinosarcoma of the endometrium
The present study immunohistochemically investigated trimethylation of lysine 27 of histone 3 (H3K27me3) expression in 769 endometrial carcinomas and 196 uterine mesenchymal tumors. One dedifferentiated endome...
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Article
Open AccessCharacteristics of submucosal leiomyomas that could cause severe hemorrhage with relugolix: an observational study
Relugolix, an oral gonadotrophin-releasing hormone receptor antagonist, was launched in Japan in 2019. Although there have been several studies on relugolix for leiomyomas, few have focused on submucosal leiom...
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Article
Open AccessImpact of lower co-payments on risk-reducing sal**o-oophorectomy and BRCA testing in Japan
In April 2020, insurance coverage for risk-reducing sal**o-oophorectomy (RRSO) for breast cancer patients with hereditary breast and ovarian cancer (HBOC) syndrome and BRCA testing were started in Japan. We inv...
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Article
Open AccessProbabilistic tsunami hazard assessment based on the Gutenberg–Richter law in eastern Shikoku, Nankai subduction zone, Japan
Earthquake and tsunami predictions comprise huge uncertainties, thus necessitating probabilistic assessments for the design of defense facilities and urban planning. In recent years, computer development has a...
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Article
Open AccessMOWLAS: NIED observation network for earthquake, tsunami and volcano
National Research Institute for Earth Science and Disaster Resilience (NIED) integrated the land observation networks established since the 1995 Kobe earthquake with the seafloor observation networks establish...
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Article
Open AccessXCL1 expression correlates with CD8-positive T cells infiltration and PD-L1 expression in squamous cell carcinoma arising from mature cystic teratoma of the ovary
Molecular characteristics of carcinoma arising from mature cystic teratoma of the ovary (MCT) remain unclear due to its rarity. We analyzed RNA-sequencing data of 2322 pan-cancer [1378 squamous cell carcinomas...
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Article
Open AccessA phase 2 study of intraperitoneal carboplatin plus intravenous dose-dense paclitaxel in front-line treatment of suboptimal residual ovarian cancer
We evaluated the efficacy of intraperitoneal (IP) carboplatin in combination with dose-dense paclitaxel (ddTCip) for suboptimal residual ovarian cancer.
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Article
A phase II randomized controlled study of pegylated liposomal doxorubicin and carboplatin vs. gemcitabine and carboplatin for platinum-sensitive recurrent ovarian cancer (GOTIC003/intergroup study)
To compare the efficacy, safety, and tolerability profiles of pegylated liposomal doxorubicin and carboplatin (PLDC) with those of gemcitabine and carboplatin (GC) for the treatment of patients with platinum-s...
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Chapter and Conference Paper
Analysis of a Rotating Machine Flexibly Supported by Vibration Isolating Materials
When diagnosing the vibration of a rotating machine flexibly supported by vibration isolating material, the natural frequency of the rigid body mode of the machine must be considered, in addition to the natura...
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Article
Estimating Compensation of Employees Based on Taxation Data
In this paper, we develop a novel approach to estimate the compensation of employees as a portion of Japan’s gross domestic income. The methodology is characterized by its extensive use of comprehensive taxati...
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Article
Impact of the number of removed lymph nodes on recurrence-free survival in stage I ovarian clear cell carcinoma
Although there have been several reports regarding the significance of staging lymphadenectomy for early stage ovarian clear cell carcinoma (CCC) patients, there have been few reports focusing on the number of...
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Article
Open AccessEffects of random 3D upper crustal heterogeneity on long-period (≥ 1 s) ground-motion simulations
The effects of the short-wavelength heterogeneity of the crustal structure on predicted ground motion at periods of 1 s and longer were investigated by conducting three-dimensional finite-difference simulation...
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Article
Open AccessAn open-label, randomized, phase II trial evaluating the efficacy and safety of standard of care with or without bevacizumab in platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer patients previously treated with bevacizumab for front-line or platinum-sensitive ovarian cancer: rationale, design, and methods of the Japanese Gynecologic Oncology Group study JGOG3023
We present the study rationale and design of the JGOG3023 study, an open-label, parallel-arm, randomized, phase II trial that aimed to assess the efficacy and safety of chemotherapy with or without bevacizumab...
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Chapter
Effect of Roughness on Ellipsometry Analysis
In spectroscopic ellipsometry (SE), appropriate modeling of surface roughness structures is critical for the accurate characterization of optical constants. In particular, when a simple SE analysis is performe...
