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Article
Open AccessUtility of a rapid assay for prostaglandin E-major urinary metabolite as a biomarker in pediatric ulcerative colitis
Prostaglandin E-major urinary metabolite (PGE-MUM) is a urinary biomarker reflecting ulcerative colitis (UC) activity. This prospective observational study aimed to evaluate the usefulness of PGE-MUM via rapid...
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Article
Clinical outcome of ulcerative colitis with severe onset in children: a multicenter prospective cohort study
As best practices for treating children with severe-onset ulcerative colitis remain controversial in the era of biologic agents, we prospectively investigated treatments and outcomes in a multicenter cohort.
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Article
Open AccessCorrection to: Expert consensus on vaccination in patients with inflammatory bowel disease in Japan
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Article
Open AccessExpert consensus on vaccination in patients with inflammatory bowel disease in Japan
Immunosuppressive therapies can affect the immune response to or safety of vaccination in patients with inflammatory bowel disease (IBD). The appropriateness of vaccination should be assessed prior to the init...
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Article
Both fecal calprotectin and fecal immunochemical tests are useful in children with inflammatory bowel disease
Noninvasive biomarkers of intestinal inflammation can reduce the number of endoscopies in children with inflammatory bowel disease (IBD). This study aimed to prospectively investigate the usefulness of fecal c...
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Article
Open AccessA review on the current status and definitions of activity indices in inflammatory bowel disease: how to use indices for precise evaluation
Many clinical trials have been conducted for inflammatory bowel disease (IBD), so various clinical indices (CIs) and endoscopic indices (EIs) have also been evaluated. However, recently, with the progress of I...
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Article
Multicenter, cross-sectional, observational study on Epstein–Barr viral infection status and thiopurine use by age group in patients with inflammatory bowel disease in Japan (EBISU study)
The Epstein–Barr virus (EBV) infection status in patients with inflammatory bowel disease (IBD), particularly those using thiopurines, may be associated with the risk of lymphoproliferative disorder and hemoph...
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Article
Open AccessStool preparation under anaerobic conditions contributes to retention of obligate anaerobes: potential improvement for fecal microbiota transplantation
Fecal microbiota transplantation (FMT) in patients with ulcerative colitis has shown variable efficacy depending on the protocol used. A previous randomized controlled trial reported that anaerobic preparation...
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Article
Severe Liver Disorder Following Liver Transplantation in STING-Associated Vasculopathy with Onset in Infancy
STING-associated vasculopathy with onset in infancy (SAVI) is a type-I interferonopathy, characterized by systemic inflammation, peripheral vascular inflammation, and pulmonary manifestations. There are three ...
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Article
Open AccessNovel TNFAIP3 microdeletion in a girl with infantile-onset inflammatory bowel disease complicated by a severe perianal lesion
A20 haploinsufficiency (HA20), a disease caused by loss-of-function TNFAIP3 mutations, manifests various autoinflammatory and/or autoimmune symptoms. Some cases of HA20 were initially diagnosed as very early onse...
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Article
Adverse events in patients with ulcerative colitis treated with indigo naturalis: a Japanese nationwide survey
Although indigo naturalis (IN) is effective for patients with active ulcerative colitis (UC), IN was associated with adverse events (AEs), including pulmonary arterial hypertension (PAH). Our aim was to evalua...
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Article
Open AccessCurrent role of colonoscopy in infants and young children: a multicenter study
To evaluate the role of colonoscopy in infants and young children and clarify the distribution of colonoscopy-requiring diseases in this age group.
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Article
Optimal Approximation Algorithms for Maximum Distance-Bounded Subgraph Problems
In this paper we study the (in)approximability of two distance-based relaxed variants of the maximum clique problem (Max Clique), named Max d-Clique and Max d-Club: A d-clique in a graph
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Article
Increased pulse wave velocity in patients with acute lacunar infarction doubled the risk of future ischemic stroke
The aim of this study was to determine whether pulse wave velocity (PWV), a marker of vascular endothelial impairment and arteriosclerosis, predicts future ischemic stroke in patients who developed acute lacun...
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Article
Open AccessGene expression profiles of mucosal biopsy specimens in children with eosinophilic gastritis
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Article
Comparison of arteriosclerotic indicators in patients with ischemic stroke: ankle–brachial index, brachial–ankle pulse wave velocity and cardio–ankle vascular index
The ankle–brachial index (ABI), brachial–ankle pulse wave velocity (baPWV) and cardio–ankle vascular index (CAVI) are surrogate markers of arteriosclerosis. However, their roles in patients with acute ischemic...
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Chapter and Conference Paper
Optimal Approximation Algorithms for Maximum Distance-Bounded Subgraph Problems
A d-clique in a graph \(G = (V, E)\) G ...
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Article
Silent brain infarct is independently associated with arterial stiffness indicated by cardio-ankle vascular index (CAVI)
It is still unclear whether silent brain infarct (SBI) and white-matter hyperintensities (WMHs) on magnetic resonance imaging (MRI) scans are associated with cardio-ankle vascular index (CAVI), a novel paramet...
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Chapter and Conference Paper
Estimation of Total Heat Leak into a Cryostat of Prospective Power Transmission Model System Integrated under Superconducting Environment (PROMISE)
Total heat leak into a cryostat of a “Prospective Power Transmission Model System Integrated under Superconducting Environment” is theoretically estimated to be 41.5W under no load condition. This magnitude is...
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Chapter and Conference Paper
Difference of the Quench Current Level of A Multi-Twisted Superconducting Cable Due to The Direction of The Applied Magnetic Field
The quench current level of a multi-twisted a.c. superconducting cable are measured as a function of the strength of the magnetic field, which is applied in the same, perpendicular or opposite direction to tha...
