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Depressor effects and pharmacokinetics of single and consecutive doses of delapril in hypertensive patients with normal or impaired renal function
The antihypertensive effects and pharmacokinetic properties of delapril, an angiotensin-converting enzyme (ACE) inhibitor, were investigated in hypertensive patients with normal renal function (NRF; n=6) and i...
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Enzymatic Studies with Renin Substrate
The contribution of renin substrate to the in vivo rate of angiotensin I production has recently gained further significance with the determination of the kinetic parameters of the renin reaction [1, 2]. Under no...