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Article
Generation of functional oocytes from male mice in vitro
Sex chromosome disorders severely compromise gametogenesis in both males and females. In oogenesis, the presence of an additional Y chromosome or the loss of an X chromosome disturbs the robust production of o...
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Article
Open AccessThe effects of pregnancy discrimination on postpartum depressive symptoms: a follow-up study
Pregnancy discrimination in the workplace is prevalent worldwide. However, few studies have examined the effects of pregnancy discrimination on mothers’ perinatal mental health. We aimed to investigate the ass...
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Article
Open AccessExploration of serum biomarkers in dogs with malignant melanoma receiving anti-PD-L1 therapy and potential of COX-2 inhibition for combination therapy
Immune checkpoint inhibitors (ICIs) such as anti-PD-L1 antibodies are widely used to treat human cancers, and growing evidence suggests that ICIs are promising treatments for canine malignancies. However, only...
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Article
Construction of a linear K-system in Hamiltonian Floer theory
The notion of linear K-system was introduced by the present authors as an abstract model arising from the structure of compactified moduli spaces of solutions to Floer’s equation in the book (Fukaya et al. in ...
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Chapter
Construction of a linear K-system in Hamiltonian Floer theory
The notion of linear K-system was introduced by the present authors as an abstract model.
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Article
One-year limb outcome and mortality in patients undergoing revascularization therapy for acute limb ischemia: short-term results of the Edo registry
The present study aimed to clarify the current status, therapeutic strategy, and 1-year outcome in acute limb ischemia (ALI) patients in Japan. The EnDOvascular treatment (Edo) registry database includes 324 p...
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Article
Open AccessPD-L1 immunohistochemistry for canine cancers and clinical benefit of anti-PD-L1 antibody in dogs with pulmonary metastatic oral malignant melanoma
Immunotherapy targeting programmed cell death 1 (PD-1) and PD-ligand 1 (PD-L1) represents promising treatments for human cancers. Our previous studies demonstrated PD-L1 overexpression in some canine cancers, ...
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Chapter
Why Japan Is No-Longer a Front-Runner: Domestic Politics, Renewable Energy, and Climate Change Policy
Why is Japan so reluctant to take a leadership role in global climate change negotiations and is trailing in the development of renewable energy? This chapter argues that the source of Japan’s inaction in clim...
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Chapter
Notations and Conventions
We use ‘hat’ such as U ^ \(\widehat {\mathcal U}\) , f ^ \(\widehat {f}\) , 𝔖 ^ \(\widehat {\mathfrak S}\) , h ^ \(\widehat {h}\) for an object defined on a Kuranishi ...
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Chapter
Composition of KG-and GG-Embeddings: Proof of Lemma 3.34
Proof of Lemma 3.34
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Chapter
Local System and Smooth Correspondence in de Rham Theory with Twisted Coefficients
Let ℒ \(\mathcal L\) be a local system, i.e., a flat vector bundle, on a manifold M. We denote by ( Ω • ( M ; ℒ ) = Γ ( M ; ∧ • T ∗ M ⊗ ℒ ) , d = d ℒ ) $$(\Omega ^{\bullet }(...
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Chapter
Global Quotients and Orbifolds
In some of our earlier writings we assumed that a Kuranishi neighborhood is not only an orbifold but also is a quotient of a manifold by a finite group action globally. We explain that there is no difference b...
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Chapter
Linear K-Systems: Floer Cohomology III – Morse Case by Multisection
In this chapter we provide the way we associate Floer cohomology with ground ring ℚ \({\mathbb Q}\) to a linear K-system when the critical submanifolds are 0-dimensional.
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Chapter
Corner Smoothing and Composition of Morphisms
The goal of this chapter is to define composition of morphisms of linear K-systems (Lemma-Definition 18.37) and to show that it is associative (Proposition 18.41). There are two key ingredients for the constru...
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Chapter
Tree-Like K-Systems: A ∞ Structure II – Proof
In this chapter we prove Theorem 21.35. The proof is mostly parallel to the proofs given in Chap. 19, and also similar to those given in [FOOO4, Subection 7.2], [Fuk4].
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Chapter
Covering Space of Effective Orbifolds and K-Spaces
We first define the notion of a covering space of an orbifold. Let U 1, U 2 be orbifolds and let π : U 1 → U 2 be a continuous map between their underlying topological spaces.
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Chapter
Fiber Product of Kuranishi Structures
Before studying fiber products we consider direct products. Let X i, i = 1, 2 be separable metrizable spaces, Z i ⊆ X i compact subsets, and U ^ i \(\widehat {\mathcal U}_i\) Kuranishi structure...
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Chapter
Stratified Submersion to a Manifold with Corners
In Definition 3.44 we defined the notions of a strongly smooth map and weakly submersive map from a K-space to a manifold without boundary or corners. In this chapter we give the corresponding definitions for ...
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Chapter
Multivalued Perturbations
We next define the notion of multivalued perturbations associated to a given good coordinate system.
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Chapter
Stokes’ Formula
In this chapter, we state and prove Stokes’ formula. We first discuss the notion of a boundary or a corner of an orbifold and of a Kuranishi structure in more detail. The discussion below is a detailed version...
