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  1. No Access

    Article

    Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model

    Efficient systemic siRNA delivery to cells in the target tissue is a current critical challenge in the drug delivery field. Several studies have demonstrated that nanoparticles such as polyethylene glycol (PEG...

    Tatsuaki Tagami, Amr S. Abu Lila… in Drug Delivery and Translational Research (2012)

  2. No Access

    Article

    Argonaute2 is a potential target for siRNA-based cancer therapy for HT1080 human fibrosarcoma

    Small interfering RNAs (siRNAs) are small RNA molecules that have a potent, sequence-specific gene silencing effect and therefore show promise for therapeutic use as molecular-targeted drugs for the treatment ...

    Tatsuaki Tagami, Takuya Suzuki, Kiyomi Hirose… in Drug Delivery and Translational Research (2011)