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  1. No Access

    Article

    Partial Acquisition of Spectral Projections Accelerates Four-dimensional Spectral-spatial EPR Imaging for Mouse Tumor Models: A Feasibility Study

    Our study aimed to accelerate the acquisition of four-dimensional (4D) spectral-spatial electron paramagnetic resonance (EPR) imaging for mouse tumor models. This advancement in EPR imaging should reduce the a...

    Misa Oba, Mai Taguchi, Yohei Kudo, Koya Yamashita in Molecular Imaging and Biology (2024)

  2. Article

    Open Access

    Correction: CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma

    Yozo Mitsui, Inik Chang, Shinichiro Fukuhara, Miho Hiraki, Naoko Arichi in BMC Cancer (2022)

  3. No Access

    Article

    Effects of Ultraviolet Rays on L-Band In Vivo EPR Dosimetry Using Tooth Enamel

    L-band electron paramagnetic resonance (EPR) in vivo dosimetry has the potential advantage of being able to accurately and sensitively measure the absorbed dose of ionizing radiation by measurements of teeth i...

    Yasuhiro Nakai, Ichiro Yamaguchi, Hiroshi Hirata in Applied Magnetic Resonance (2022)

  4. No Access

    Article

    RF/Microwave Resonators for Preclinical and Clinical EPR Applications: Current Status and Challenges

    This article reviews the current status and challenges of using RF/microwave resonators for electron paramagnetic resonance (EPR) spectroscopy and imaging from the viewpoint of preclinical and clinical applica...

    Hiroshi Hirata, Harold M. Swartz in Applied Magnetic Resonance (2022)

  5. Article

    Open Access

    Inhibitory effect of Citrus flavonoids on the in vitro transport activity of human urate transporter 1 (URAT1/SLC22A12), a renal re-absorber of urate

    As hyperuricemia is a cause of urate-related diseases such as gout, the anti-hyperuricemic and/or uricosuric activity of food ingredients is receiving increased attention. Here, we examined the inhibitory acti...

    Yu Toyoda, Tappei Takada, Hiroki Saito, Hiroshi Hirata in npj Science of Food (2020)

  6. No Access

    Chapter

    Resonators for Clinical Electron Paramagnetic Resonance (EPR)

    In pulsed electron paramagnetic resonance (EPR), free-induction decay (FID) or spin echo (SE) signals of unpaired electrons are recorded in the time-domain. In both methods, electromagnetic waves play an impor...

    Hiroshi Hirata, Sergey Petryakov in Measuring Oxidants and Oxidative Stress in… (2020)

  7. No Access

    Article

    Impact of the Characteristic Impedance of Coaxial Lines on the Sensitivity of a 750-MHz Electronically Tunable EPR Resonator

    A 750-MHz electronically tunable resonator was investigated in terms of the sensitivity of electron paramagnetic resonance (EPR) signal detection. The conversion efficiency of the radio-frequency magnetic fiel...

    Ririko Nakaoka, Denis A. Komarov, Shingo Matsumoto in Applied Magnetic Resonance (2018)

  8. No Access

    Article

    Feasibility of in vivo three-dimensional T 2 * map** using dicarboxy-PROXYL and CW-EPR-based single-point imaging

    The aim of this study was to demonstrate the feasibility of in vivo three-dimensional (3D) relaxation time T 2 * map** of a dicarboxy-PROXYL radical us...

    Harue Kubota, Denis A. Komarov in Magnetic Resonance Materials in Physics, B… (2017)

  9. Article

    Open Access

    Seasonal induction of alternative principal pathway for rose flower scent

    Ecological adaptations to seasonal changes are often observed in the phenotypic traits of plants and animals and these adaptations are usually expressed through the production of different biochemical end prod...

    Hiroshi Hirata, Toshiyuki Ohnishi, Kensuke Tomida, Haruka Ishida in Scientific Reports (2016)

  10. Article

    Open Access

    CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma

    Cytochrome P450 1B1 (CYP1B1) has been shown to be up-regulated in many types of cancer including renal cell carcinoma (RCC). Several reports have shown that CYP1B1 can influence the regulation of tumor develop...

    Yozo Mitsui, Inik Chang, Shinichiro Fukuhara, Miho Hiraki, Naoko Arichi in BMC Cancer (2015)

  11. No Access

    Article

    Passive Decoupling Due to Low Q-Factors of Four-Channel Coils in 300-MHz Pulsed EPR Imaging

    This article describes a four-channel coil array for in vivo time-domain electron paramagnetic resonance (EPR) imaging applications. Decoupling of the individual element coils was achieved with the low-quality...

    Ayano Enomoto, Keita Saito, Sankaran Subramanian in Applied Magnetic Resonance (2015)

  12. No Access

    Article

    Cytochrome P450 1B1 polymorphisms and risk of renal cell carcinoma in men

    The cytochrome P450 1B1 (CYP1B1) enzyme activates xenobiotics to reactive forms as well as convert estradiol to 4-hydroxy-estradiol that has been shown to play a role in the carcinogenesis process of the kidne...

    Inik Chang, Shinichiro Fukuhara, Darryn K. Wong, Ankurpreet Gill in Tumor Biology (2014)

  13. No Access

    Article

    Proton-Electron Double-Resonance Imaging of pH Using Phosphonated Trityl Probe

    Variable radio frequency proton-electron double-resonance imaging (VRF PEDRI) enables extracting a functional map from a limited number of images acquired at pre-selected EPR frequencies using specifically des...

    Wataru Takahashi, Andrey A. Bobko, Ilirian Dhimitruka in Applied Magnetic Resonance (2014)

  14. No Access

    Chapter

    MicroRNAs in the Development and Progression of Kidney Cancer

    Renal cell carcinoma (RCC), a genetically and histopathologically heterogeneous disorder, is the most lethal of all genitourinary cancers and is generally refractory to current treatment regimens, including ch...

    Sharanjot Saini, Sumit Arora, Shahana Majid in MicroRNA in Development and in the Progres… (2014)

  15. No Access

    Article

    Ozone-Assisted Catalysis of Toluene with Layered ZSM-5 and Ag/ZSM-5 Zeolites

    This paper presents a new type of ozone-assisted catalysis for toluene decomposition. The different catalytic activities of ZSM-5 and Ag/ZSM-5 were incorporated into a layered catalyst with a tandem configurat...

    Hyun-Ha Kim, Masami Sugasawa, Hiroshi Hirata in Plasma Chemistry and Plasma Processing (2013)

  16. No Access

    Chapter

    Changes in phosphorus compounds around the rhizosphere of groundnut and pigeonpea grown in an Andosol with arbuscular mycorrhizal fungi

    A pot experiment was conducted with an Andosol to investigate the changes of phosphorus(P) compounds in the rhizosphere and hyphesphere soil (Organic P, Ca-P, Al-P, Fe-P). To distinguish between the effect of ...

    Naoko Suzuki, Hiroshi Hirata in Plant Nutrition for Sustainable Food Produ… (1997)

  17. No Access

    Article

    Analytical study of a cadmium ion-selective ceramic membrane electrode

    Die Membran wurde durch Pressen von Cd-, Ag und Cu(I)-sulfid bei 200–500°C und 3–7 t/cm2 hergestellt. Die beste Ansprechempfindlichkeit ergab sich bei einem Gehalt von <30% Cu2S und >5% CdS. Die Nernstsche Gleich...

    Hiroshi Hirata, Kenji Higashiyama in Fresenius' Zeitschrift für analytische Chemie (1971)