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Open AccessCervical percutaneous interferential current stimulation improves citric acid cough tests in patients with Parkinson’s disease on medication
Aspiration pneumonia is the leading cause of death in patients with Parkinson’s disease. The incidence of silent aspiration is high in such patients owing to decreased pharyngeal and laryngeal sensation; thus,...
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Article
Open AccessTranscutaneous auricular vagus nerve stimulation enhances short-latency afferent inhibition via central cholinergic system activation
The present study examined the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on short-latency afferent inhibition (SAI), as indirect biomarker of cholinergic system activation. 24 healthy...
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Article
Open AccessAssociation between motor symptoms of Parkinson’s disease and swallowing disorders
Parkinson’s disease (PD) presents with motor symptoms that hinder physical activity. This study aimed to thoroughly investigate swallowing dysfunction in patients with PD using videofluoroscopy (VF) and the Mo...
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Article
Open AccessProgressive multifocal leukoencephalopathy associated with systemic lupus erythematosus: longitudinal observation of lymphocytes, JC virus in cerebrospinal fluid, and brain magnetic resonance imaging
Progressive multifocal leukoencephalopathy (PML) rarely occurs in patients with systemic lupus erythematosus (SLE). This report presents the case of a patient who developed PML due to SLE-associated multiple f...
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Article
Detection of episodic nocturnal hypercapnia in patients with neurodegenerative disorders
Episodic nocturnal hypercapnia (eNH) in transcutaneous carbon dioxide pressure (PtcCO2) corresponding to rapid eye movement sleep hypoventilation is a useful biomarker for detecting nocturnal hypoventilation. How...
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Open AccessThe long-term effects of heated tobacco product exposure on the central nervous system in a mouse model of prodromal Alzheimer's disease
Heated tobacco products (HTPs) have emerged as novel alternatives to conventional cigarettes (CCs), marketed by the tobacco industry as having a reduced potential for harm. Nevertheless, a significant dearth o...
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Article
Acute Amnesic Symptoms Due to Bilateral Fornix Column Infarction: a Case Report
The fornix is a part of the Papez circuit and associated with memory formation. Pure fornix infarction is a very rare type of stroke that causes symptoms such as transient global amnesia (TGA); however, the de...
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Article
Peak expiratory flow, but not tongue pressure, can predict pneumonia development in older adults
We investigated whether tongue pressure and peak expiratory flow, which are associated with swallowing dysfunction and disability to expectorate sputum, could predict pneumonia development in older adults.
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Article
Extubation failure due to atypical parkinsonism with negligible motor and variable non-motor symptoms associated with a variant of DCTN1
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Article
Levetiracetam-induced myoclonus following recovery from non-convulsive status epilepticus in an elderly woman
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Article
Various effects of nutritional status on clinical outcomes after intracerebral hemorrhage
Although the assessment of nutrition is essential for stroke patients, detailed associations between nutritional status at admission, subsequent complications, and clinical outcomes in patients with acute intr...
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Article
Clinical characteristics and tumor markers in ischemic stroke patients with active cancer
Cancer-associated ischemic stroke (CAS) refers to a hypercoagulation disorder related to malignant tumors, especially adenocarcinoma. Carbohydrate antigen (CA) 125 is a mucinous serum marker that might reflect...
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Article
Open AccessCorrection to: FXTAS is difficult to differentiate from neuronal intranuclear inclusion disease through skin biopsy: a case report
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessFXTAS is difficult to differentiate from neuronal intranuclear inclusion disease through skin biopsy: a case report
Both fragile X-associated tremor/ataxia syndrome (FXTAS) and late-onset neuronal intranuclear inclusion disease (NIID) show CGG/GGC trinucleotide repeat expansions. Differentiating these diseases are difficult...
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Article
Association between stroke lesions and videofluoroscopic findings in acute stroke patients
We aimed to assess stroke lesions, which play a key role in determining swallowing dysfunction, and findings of videofluoroscopy (VF), which provides the most accurate instrumental assessment for evaluating sw...
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Article
Open AccessZonisamide can ameliorate the voltage-dependence alteration of the T-type calcium channel CaV3.1 caused by a mutation responsible for spinocerebellar ataxia
Spinocerebellar ataxia (SCA) 42 is caused by a mutation in CACNA1G, which encodes the low voltage-gated calcium channel CaV3.1 (T-type). Patients with SCA42 exhibit a pure form of cerebellar ataxia. We encountere...
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Open AccessLobar microbleeds are associated with cognitive impairment in patients with lacunar infarction
Associations between cognitive decline and cerebral microbleeds (CMBs) have received increasing attention. An association between CMB distribution (deep or lobar) and cognitive decline has been reported, but t...
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Article
Pomalidomide-associated progressive multifocal leukoencephalopathy in multiple myeloma: cortical susceptibility-weighted imaging hypointense findings prior to clinical deterioration
Although there are several case reports of progressive multifocal leukoencephalopathy (PML) in multiple myeloma (MM), there are few reports of cases associated with pomalidomide. Here, we report the case of a ...
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Article
Open AccessIncreased blood pressure variability during the subacute phase of ischemic stroke is associated with poor functional outcomes at 3 months
Thus far, it is well known that increased blood pressure variability may exacerbate stroke outcomes. Blood pressure in the acute phase would be influenced by both reactive hypertension to stroke and intrinsic ...
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Article
Open AccessEffects of controlled abnormal joint movement on the molecular biological response in intra-articular tissues during the acute phase of anterior cruciate ligament injury in a rat model
The anterior cruciate ligament (ACL) is responsible for braking forward movement of the tibia relative to the femur and for tibial rotation. After ACL injury, this braking performance deteriorates, inducing ab...
