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Article
Surgery for spina bifida occulta: spinal lipoma and tethered spinal cord
The technical evolution of the surgery for spina bifida occulta (SBO) over the course of a half-century was reviewed with special foci placed on the spinal lipoma and tethered spinal cord. Looking back through...
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Article
A long-term survivor of pediatric midline glioma with H3F3A K27M and BRAF V600E double mutations
We report a case of 2-year-old female with lateral ventricular glioma harboring both H3F3A K27M and BRAF V600E mutations. By the methylation analysis, the tumor was classified as a diffuse midline glioma H3 K27M ...
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Article
Review of ependymomas: assessment of consensus in pathological diagnosis and correlations with genetic profiles and outcome
We focused on histological and immunohistochemical characteristics of ependymoma (EPN) with molecular profiles to develop more reproducible criteria of the diagnosis. Three expert neuropathologists reviewed th...
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Article
Identification of a novel KLC1–ROS1 fusion in a case of pediatric low-grade localized glioma
The proto-oncogene tyrosine-protein kinase ROS1 (ROS1) is a tyrosine kinase that is closely related to anaplastic lymphoma kinase receptor (ALK). We describe a novel KLC1–ROS1 fusion identified in a case of pedia...
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Article
Prof. Satoshi Matsumoto eulogy
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Article
Pediatric thalamic glioma with H3F3A K27M mutation, which was detected before and after malignant transformation: a case report
Histone H3.3 (H3F3A) mutation in the codon for lysine 27 (K27M) has been found as driver mutations in pediatric glioblastoma and has been suggested to play critical roles in the pathogenesis of thalamic gliomas a...
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Article
Reexpandability of the ventricular system of hydrocephalic children in the event of shunt occlusion
To estimate intracranial volume-buffering capacity in the event of shunt occlusion, the reexpandabilty of the lateral ventricles and clinical manifestations were examined in shunt-dependent hydrocephalic child...