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  1. Article

    Open Access

    Calcium-mediated rapid movements defend against herbivorous insects in Mimosa pudica

    Animals possess specialized systems, e.g., neuromuscular systems, to sense the environment and then move their bodies quickly in response. Mimosa pudica, the sensitive plant, moves its leaves within seconds in re...

    Takuma Hagihara, Hiroaki Mano, Tomohiro Miura, Mitsuyasu Hasebe in Nature Communications (2022)

  2. Article

    Open Access

    A multi-site, multi-disorder resting-state magnetic resonance image database

    Machine learning classifiers for psychiatric disorders using resting-state functional magnetic resonance imaging (rs-fMRI) have recently attracted attention as a method for directly examining relationships bet...

    Saori C. Tanaka, Ayumu Yamashita, Noriaki Yahata, Takashi Itahashi in Scientific Data (2021)

  3. Article

    Open Access

    Rapid movements in plants

    Plant movements are generally slow, but some plant species have evolved the ability to move very rapidly at speeds comparable to those of animals. Whereas movement in animals relies on the contraction machiner...

    Hiroaki Mano, Mitsuyasu Hasebe in Journal of Plant Research (2021)

  4. No Access

    Article

    Calcium dynamics during trap closure visualized in transgenic Venus flytrap

    The leaves of the carnivorous plant Venus flytrap, Dionaea muscipula (Dionaea) close rapidly to capture insect prey. The closure response usually requires two successive mechanical stimuli to sensory hairs on the...

    Hiraku Suda, Hiroaki Mano, Masatsugu Toyota, Kenji Fukushima in Nature Plants (2020)

  5. Article

    Open Access

    Narrower QRS may be enough to respond to cardiac resynchronization therapy in lightweight patients

    A prolonged QRS duration (QRSd) is promising for a response to cardiac resynchronization therapy (CRT). The variation in human body sizes may affect the QRSd. We hypothesized that conduction disturbances may e...

    Toshiko Nakai, Hiroaki Mano, Yukitoshi Ikeya, Yoshihiro Aizawa in Heart and Vessels (2020)

  6. Article

    Open Access

    Brain-specific homeobox Bsx specifies identity of pineal gland between serially homologous photoreceptive organs in zebrafish

    The pineal gland functioning as a photoreceptive organ in non-mammalian species is a serial homolog of the retina. Here we found that Brain-specific homeobox (Bsx) is a key regulator conferring individuality o...

    Hiroaki Mano, Yoichi Asaoka, Daisuke Kojima, Yoshitaka Fukada in Communications Biology (2019)

  7. No Access

    Article

    The effects of standard electrical PV isolation vs. “pace and ablate” on ATP-provoked PV reconnections

    Catheter ablation procedures for atrial fibrillation (AF) often involve circumferential pulmonary vein isolation (PVI). Lack of reliable identification of conduction gaps along the ablation line necessitates a...

    Yasuo Okumura, Ichiro Watanabe in Journal of Interventional Cardiac Electrop… (2014)

  8. No Access

    Article

    Increased levels of inflammatory and extracellular matrix turnover biomarkers persist despite reverse atrial structural remodeling during the first year after atrial fibrillation ablation

    Left atrial (LA) remodeling associated with atrial fibrillation (AF) is known to be related to inflammation and collagen turnover. We investigated the changes in the biomarkers of inflammation and collagen tur...

    Naoko Sasaki, Yasuo Okumura, Ichiro Watanabe in Journal of Interventional Cardiac Electrop… (2014)

  9. No Access

    Article

    Potential anatomic substrate of peri-atrioventricular nodal atrial tachycardia ablated from the noncoronary sinus of Valsalva

    Although focal atrial tachycardia (AT) is known to sometimes be ablated from the noncoronary aortic cusp (NCC), the electro-anatomic characteristics of NCC-AT are not well known.

    Hiroaki Mano, Yasuo Okumura, Ichiro Watanabe in Journal of Interventional Cardiac Electrop… (2013)

  10. No Access

    Article

    Comparative distribution of complex fractionated atrial electrograms, high dominant frequency (HDF) sites during atrial fibrillation and HDF sites during sinus rhythm

    Complex fractionated atrial electrograms (CFAEs) and high dominant frequency sites during atrial fibrillation (AF-HDF) are related to the maintenance of atrial fibrillation (AF). HDF sites in sinus rhythm (SR-...

    Masayoshi Kofune, Yasuo Okumura in Journal of Interventional Cardiac Electrop… (2013)

  11. No Access

    Article

    Characteristics and distribution of complex fractionated atrial electrograms and the dominant frequency during atrial fibrillation: relationship to the response and outcome of circumferential pulmonary vein isolation

    Although sites of complex fractionated electrograms (CFAEs) and dominant frequency (DF) are known to be critical for the maintenance of atrial fibrillation (AF), spatial distribution of CFAEs and DF and their ...

    Yasuo Okumura, Ichiro Watanabe in Journal of Interventional Cardiac Electrop… (2012)

  12. No Access

    Article

    Effects of inter-electrode spacing on complex fractionated atrial electrograms and dominant frequency detection

    The influence of inter-electrode spacing (IES) on complex fractionated atrial electrograms (CFAEs) and dominant frequency (DF) detection was assessed.

    Koichi Nagashima, Yasuo Okumura in Journal of Interventional Cardiac Electrop… (2012)

  13. No Access

    Article

    Two novel genotypes of the thiazide-sensitive Na-Cl cotransporter (SLC12A3) gene in patients with Gitelman’s syndrome

    Gitelman’s syndrome is an autosomal recessive disorder marked by salt wasting and hypokalaemia resulting from loss-of-function mutations in the SLC12A3 gene that codes for the thiazide-sensitive Na-Cl cotransport...

    Noriko Aoi, Tomohiro Nakayama, Yoshiko Tahira, Akira Haketa, Minako Yabuki in Endocrine (2007)