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Article
Open AccessEvaluation of adenovirus capsid labeling versus transgene expression
Adenoviral vectors have been utilized for a variety of gene therapy applications. Our group has incorporated bioluminescent, fluorographic reporters, and/or suicide genes within the adenovirus genome for analy...
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Article
Open AccessGenetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy
Human adenovirus serotype 5 (Ad5) has been widely explored as a gene delivery vector for a variety of diseases. Many target cells, however, express low levels of Ad5 native receptor, the Coxsackie-Adenovirus R...
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Protocol
Derivation, Maintenance, and Induction of the Differentiation In Vitro of Equine Embryonic Stem Cells
We describe here the isolation and maintenance of pluripotent embryonic stem (ES) cells from equine blastocysts that have been frozen and thawed. Equine ES cells appear to main-tain a normal diploid karyotype ...
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Article
The coactivators p300 and CBP have different functions during the differentiation of F9 cells
We have characterized an element (differentiation response element, DRE) in the promoter region of the c-jun gene that is both necessary and sufficient for retinoic acid (RA) and adenovirus early region (E1A) me...
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Article
Assignment of the human gene for KBF2/RBP-Jk to chromosome 9p12-13 and 9q13 by fluorescencein situ hybridization
The transcription factor KBF2 has been characterized as a factor that binds to the NFkB site of mouse major histocompatibility complex (MHC) class I genes and its amino acid sequence has been shown to be ident...
