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  1. Article

    Open Access

    PAK4 inhibition augments anti-tumour effect by immunomodulation in oral squamous cell carcinoma

    Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumours, warranting novel treatments. Here, we examined the therapeutic efficacy of inhibiting p21 activated kinase 4 (PAK4) in OSCC and ...

    Danki Takatsuka, Hidetake Tachinami, Nihei Suzuki, Manabu Yamazaki in Scientific Reports (2024)

  2. Article

    Open Access

    Conventional osteosarcoma of the mandible successfully treated with radical surgery and adjuvant chemotherapy after responding poorly to neoadjuvant chemotherapy: a case report

    Osteosarcoma, the most common primary bone malignancy, has an extremely poor prognosis and a high rate of local recurrence and distal metastases. Because osteosarcomas of the head and neck region are rare, acc...

    Yutaro Kimura, Kei Tomihara, Hidetake Tachinami in Journal of Medical Case Reports (2017)